Cornélissen Germaine, Berezkin Mikhail Victorovich, Syutkina Elena V, Blank Mikhail A, Blank Olga A, Chibisov Sergei M, Halberg Franz
Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN 55455, USA.
J Exp Ther Oncol. 2006;6(1):63-72.
This paper is a memorial to Mikhail Victorovich Berezkin (MVB) (10 April 1940 - 16 January 2005), an enthusiastic advocate of chrono-oncology. It illustrates his early dose- and circadian time-response curves, limited as yet by a 4-timepoint approach, provides a list of his publications, and offers a succinct overview of individualized marker rhythm-guided oncotherapy.
本文是对米哈伊尔·维克托罗维奇·别列兹金(MVB)(1940年4月10日 - 2005年1月16日)的纪念文章,他是时辰肿瘤学的热情倡导者。文章展示了他早期的剂量和昼夜时间反应曲线(当时受四点法限制),列出了他的出版物,并简要概述了个体化标志物节律引导的肿瘤治疗。