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果蝇中结构 amy 和调节图谱变异之间的非随机关联。

Nonrandom Association between Structural Amy and Regulatory map Variants in DROSOPHILA MELANOGASTER.

机构信息

Department of Population, University of Utrecht, Padualaan 8, 3584.

出版信息

Genetics. 1986 Nov;114(3):875-84. doi: 10.1093/genetics/114.3.875.

DOI:10.1093/genetics/114.3.875
PMID:17246355
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1203018/
Abstract

Populations of Drosophila melanogaster were investigated for variation in structural Amy genes, coding for different electrophoretic variants, and regulatory genes that determine the tissue-specific production patterns of alpha-amylase in the midguts of adults and larvae. Analysis of strains homozygous for second chromosomes extracted from three cage populations of different geographical origin revealed a consistent nonrandom association between Amy and midgut activity pattern (map) variants of alpha-amylase in adults and third-instar larvae. The origin and maintenance of the linkage disequilibrium between Amy and map genes are discussed.

摘要

对黑腹果蝇的种群进行了调查，以研究结构 Amy 基因的变异，这些基因编码不同的电泳变体，以及调节基因，这些基因决定了成年和幼虫中中肠α-淀粉酶的组织特异性产生模式。对来自三个不同地理起源的笼养种群的第二染色体纯合子进行分析，揭示了 Amy 与成年和三龄幼虫中肠α-淀粉酶的活性模式（map）变体之间存在一致的非随机关联。讨论了 Amy 与 map 基因之间连锁不平衡的起源和维持。