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家族 Salmonidae 内的基因复制:二倍体遗传的两个基因座,在虹鳟鱼中被报道为四倍体。

Gene Duplication within the Family Salmonidae: Disomic Inheritance of Two Loci Reported to Be Tetrasomic in Rainbow Trout.

机构信息

College of Fisheries, University of Washington, Seattle, Washington 98195.

出版信息

Genetics. 1973 Aug;74(4):647-54. doi: 10.1093/genetics/74.4.647.

Abstract

We describe our studies of the genetics of allelic variation for NADP-dependent isocitrate dehydrogenase (IDH) in rainbow trout (Salmo gairdneri). Five populations of rainbow trout were studied to determine the phenotypic distribution of IDH; 453 progeny from a number of controlled matings were examined to determine the nature of inheritance of these alleles. The variation was found to be the result of four alleles producing protein subunits of differing electrophoretic mobilities. Progeny from crosses clearly demonstrated the presence of two disomic loci controlling the variation, rather than one tetrasomic locus as had been previously reported. These findings support our contention that the hypothesis of a tetraploid event in salmonid evolution should not be uncritically accepted.

摘要

我们描述了我们对虹鳟鱼(Salmo gairdneri)中 NADP 依赖性异柠檬酸脱氢酶(IDH)等位基因变异的遗传学研究。研究了五个虹鳟鱼种群以确定 IDH 的表型分布;检查了来自许多受控交配的 453 个后代,以确定这些等位基因的遗传性质。发现这种变异是由四个产生不同电泳迁移率的蛋白质亚基的等位基因引起的。杂交后代清楚地表明,存在两个控制变异的二倍体基因座,而不是以前报道的一个四倍体基因座。这些发现支持了我们的观点,即鲑鱼进化中的四倍体事件假说不应不加批判地接受。

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