Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Genetics. 1979 Jun;92(2):409-18. doi: 10.1093/genetics/92.2.409.
The effect of temperature and parental age on recombination frequency in C. elegans was studied between pairs of closely linked markers on linkage groups I and V. In the regions studied, recombination frequency varied three-fold over the temperature range 13.5 degrees to 26 degrees . Temperature-shift experiments indicated that a temperature-sensitive recombination event occurs approximately 50 oocytes prior to fertilization. Recombination frequency was observed to decrease with maternal age. The greatest decrease was observed in the first 24 hours of egg production. The frequency of male progeny, a measure of X-chromosome nondisjunction was also studied. This frequency increased with elevated temperature and age of the parent.
温度和父母年龄对秀丽隐杆线虫连锁群 I 和 V 上紧密连锁标记之间重组频率的影响进行了研究。在所研究的区域内，重组频率在 13.5 度到 26 度的温度范围内变化了三倍。温度转换实验表明，在受精前大约 50 个卵母细胞中发生了一个温度敏感的重组事件。观察到重组频率随母体年龄的增加而降低。在产卵的头 24 小时内观察到最大的降低。雄性后代的频率，即 X 染色体不分离的度量，也进行了研究。这个频率随着温度的升高和父母年龄的增加而增加。
