[使用不同细胞分离器进行干细胞分离]
[Stem cell separation with different cell separators].
作者信息
Eckstein R, Weisbach V, Zeiler T, Holfeld-Ozuysal C, Zimmermann R, Heuft H G, Zingsem J
机构信息
Abteilung Innere Medizin und Poliklinik m.S. Hämatologie und Onkologie, Untersitätsklinikum Rudolf Virchow, Berlin.
出版信息
Beitr Infusionsther. 1991;28:247-50.
For some years, there has been an increasing success in transplanting peripheral blood stem cells (PBSC) instead of autologous bone marrow in patients suffering from different malignancies. While collecting PBSC for autologous transplantation, we compared four different separation techniques and three different cell separators (COBE Spectra, Fresenius AS 104, Haemonetics V50) routinely used for platelet production. Our results suggest that continuous flow separators seem to have some advantage over discontinuous flow machines in harvesting PBSC.
多年来，在患有不同恶性肿瘤的患者中，移植外周血干细胞（PBSC）而非自体骨髓的成功率一直在提高。在为自体移植采集外周血干细胞时，我们比较了常用于血小板生产的四种不同分离技术和三种不同的细胞分离器（COBE Spectra、费森尤斯AS 104、血液技术公司V50）。我们的结果表明，在采集外周血干细胞方面，连续流动分离器似乎比间断流动机器具有一些优势。
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