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腹腔镜胆囊切除术中胆管损伤:单机构的初步及长期结果

Bile duct injuries during laparoscopic cholecystectomy: primary and long-term results from a single institution.

作者信息

Karvonen Jukka, Gullichsen Risto, Laine Simo, Salminen Paulina, Grönroos Juha M

机构信息

Department of Surgery, University of Turku, Turku, Finland.

出版信息

Surg Endosc. 2007 Jul;21(7):1069-73. doi: 10.1007/s00464-007-9316-7. Epub 2007 May 19.

Abstract

BACKGROUND

Iatrogenic bile duct injury carries high morbidity. After the introduction of laparoscopic cholecystectomy the incidence of these injuries has at least doubled, and even after the learning curve, the incidence has plateaued at the level of 0.5%.

METHODS

A total of 32 patients sustained biliary tract injuries of the 3736 laparoscopic cholecystectomies performed in and around Turku University Central Hospital between January 1995 and April 2002. The data concerning primary treatment and long-term results were collected and analyzed retrospectively.

RESULTS

The overall incidence for bile duct injuries, including all the minor injuries (cystic duct leaks and bile duct strictures), was 0.86%; for major injuries alone the incidence was 0.38%. Nineteen percent of the injuries were detected intraoperatively. All the cystic duct leaks were treated endoscopically with a 90% success rate. Of the bile duct strictures 88% were treated successfully with endoscopic techniques. Ninety-three percent of the major injuries, including tangential lesions of common bile duct and total transections, were treated operatively. The operation of choice was either hepaticojejunostomy or cholangiojejunostomy in 69% of the cases; the rest were treated with simple suturing over a T-tube or an endoscopically placed stent. The long-term results, with a median follow-up period of 7.5 years, are good in 79% of the operated patients and in 84% of the whole study population. Mortality rate was 3% and acute or chronic cholangitis was seen in 13% of the patients during follow-up.

CONCLUSION

Most of the minor bile duct injuries, including cystic duct leaks and bile duct strictures, are well treatable with endoscopic techniques, whereas most of the major injuries require operative treatment, which at optimal circumstances gives good results.

摘要

背景

医源性胆管损伤的发病率很高。自从腹腔镜胆囊切除术应用以来,此类损伤的发生率至少增加了一倍,即便度过了学习曲线阶段,其发生率仍稳定在0.5%的水平。

方法

1995年1月至2002年4月期间,图尔库大学中心医院及其周边地区共进行了3736例腹腔镜胆囊切除术,其中32例患者发生了胆道损伤。回顾性收集并分析了有关初始治疗及长期结果的数据。

结果

胆管损伤的总体发生率,包括所有轻微损伤(胆囊管漏和胆管狭窄)为0.86%;仅严重损伤的发生率为0.38%。19%的损伤在术中被发现。所有胆囊管漏均通过内镜治疗,成功率为90%。88%的胆管狭窄通过内镜技术成功治疗。93%的严重损伤,包括胆总管切线伤和完全横断伤,接受了手术治疗。69%的病例首选肝空肠吻合术或胆管空肠吻合术;其余病例采用T管上简单缝合或内镜放置支架治疗。中位随访期为7.5年,79%的手术患者和84%的整个研究人群长期结果良好。死亡率为3%,随访期间13%的患者出现急性或慢性胆管炎。

结论

大多数轻微胆管损伤,包括胆囊管漏和胆管狭窄,采用内镜技术治疗效果良好,而大多数严重损伤需要手术治疗,在最佳情况下手术效果良好。

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