He Gui-zhen, Cui Xiao-yu, Dong Liang-guang
Department of Parenteral and Enteral Nutrition, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2006 Dec;28(6):853-7.
In the past decade, the focus of nutritional study shifted from epidemiology and physiology to molecular biology. Advanced research strategies and technologies including genomics, transcriptomics, proteomics, metabolomics, and system biology have been gradually applied in clinical nutrition. This article reviews the effects of nutrients on gene expressions, application of modern molecular biology in clinical nutrition, as well as the advances and challenges in recent years..
在过去十年中，营养研究的重点从流行病学和生理学转向了分子生物学。包括基因组学、转录组学、蛋白质组学、代谢组学和系统生物学在内的先进研究策略和技术已逐渐应用于临床营养领域。本文综述了营养素对基因表达的影响、现代分子生物学在临床营养中的应用，以及近年来的进展和挑战。
