2002 - 2004年疫情期间，巴西北部地区登革热病毒3型基因型III和V共同传播的证据。
Evidence for the co-circulation of dengue virus type 3 genotypes III and V in the Northern region of Brazil during the 2002-2004 epidemics.
作者信息
Nogueira Meri Bordignon, Stella Vanessa, Bordignon Juliano, Batista Weber Cheli, Borba Luana de, Silva Luis Hildebrando Pereira da, Hoffmann Federico Guillermo, Probst Christian Macagnan, Santos Claudia Nunes Duarte dos
机构信息
Instituto Carlos Chagas, Curitiba, PR, Brasil.
出版信息
Mem Inst Oswaldo Cruz. 2008 Aug;103(5):483-8. doi: 10.1590/s0074-02762008000500013.
The reintroduction of dengue virus type 3 (DENV-3) in Brazil in 2000 and its subsequent spread throughout the country was associated with genotype III viruses, the only DENV-3 genotype isolated in Brazil prior to 2002. We report here the co-circulation of two different DENV-3 genotypes in patients living in the Northern region of Brazil during the 2002-2004 epidemics. Complete genomic sequences of viral RNA were determined from these epidemics, and viruses belonging to genotypes V (Southeast Asia/South Pacific) and III were identified. This recent co-circulation of different DENV-3 genotypes in South America may have implications for pathological and epidemiological dynamics.
2000年，3型登革病毒（DENV-3）重新引入巴西，随后在全国传播，这与III型基因型病毒有关，该基因型是2002年之前在巴西分离出的唯一DENV-3基因型。我们在此报告，在2002 - 2004年疫情期间，巴西北部地区的患者中两种不同的DENV-3基因型共同流行。从这些疫情中确定了病毒RNA的完整基因组序列，并鉴定出属于V型（东南亚/南太平洋）和III型的病毒。最近在南美洲不同DENV-3基因型的这种共同流行可能对病理和流行病学动态产生影响。
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