监测异基因干细胞移植后免疫固定电泳结果呈阴性的多发性骨髓瘤患者的血清游离轻链。
Monitoring serum free light chains in patients with multiple myeloma who achieved negative immunofixation after allogeneic stem cell transplantation.
作者信息
Mösbauer Ulrike, Ayuk Francis, Schieder Heike, Lioznov Michael, Zander Axel R, Kröger Nicolaus
出版信息
Haematologica. 2007 Feb;92(2):275-6. doi: 10.3324/haematol.10568.
PMID:17296589
Abstract
Monitoring of serum free immunoglobulin light chains (FLC) in 26 myeloma patients who achieved immunofixation negativity after allografting showed a decrease of FLC at a median of 128 days before immunofixation negativity. In patients who subsequently relapsed, a 25% increase of FLC was observed at a median of 98 days before immunofixation positivity.
摘要
对26例移植后实现免疫固定阴性的骨髓瘤患者进行血清游离免疫球蛋白轻链（FLC）监测，结果显示在免疫固定阴性前中位数128天时FLC下降。在随后复发的患者中，在免疫固定阳性前中位数98天时观察到FLC增加了25%。
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