韩国基因组流行病学研究中食物频率问卷的验证与可重复性

Validation and reproducibility of food frequency questionnaire for Korean genome epidemiologic study.

作者信息

Ahn Y, Kwon E, Shim J E, Park M K, Joo Y, Kimm K, Park C, Kim D H

机构信息

Center for Genomic Science, National Institute of Health, Center for Disease Control and Prevention, Seoul, Korea.

出版信息

Eur J Clin Nutr. 2007 Dec;61(12):1435-41. doi: 10.1038/sj.ejcn.1602657. Epub 2007 Feb 7.

DOI:10.1038/sj.ejcn.1602657

PMID:17299477

Abstract

OBJECTIVE

To evaluate validity and reliability of the food-frequency questionnaire (FFQ) developed for the Korean Genome Epidemiologic Study (KoGES).

METHODS

FFQ was administered twice at 1-year interval (first FFQ (FFQ1) at the beginning and second FFQ (FFQ2) at the end of the study) and diet records (DRs) were collected for 3 days during each of the four seasons from December 2002 to May 2004 for those who attended the health examination center. At the end of the study period, we collected the 12-day DRs of 124 participants. The nutrient intakes from the DRs were compared with both FFQ1 and FFQ2.

RESULTS

The intakes of energy and some nutrients estimated from FFQ1 and FFQ2 were different from those assessed by the DRs. Especially, the consumption of carbohydrates was higher in FFQ1 and FFQ2 than in the DRs. The de-attenuated, age, sex and energy intake adjusted correlation coefficients between the FFQ2 and the 12-day DRs in Korean population ranged between 0.23 (Vitamin A) and 0.64 (carbohydrate). The median for all nutrients was 0.39. The correlations were similar when we compared nutrient densities of both methods. Joint classification of calorie-adjusted nutrient intakes assessed by FFQ2 and 12-day DRs by quartile ranged from 25.8% (vitamin A) to 39.5% (carbohydrate, iron) for exact concordance. Except vitamin A, the proportion of subjects classified into distant quartile was less than 7% in all nutrients. The median of correlations between the two FFQs 1 year apart were 0.45 for all nutrient intakes and 0.39 for nutrient densities.

CONCLUSIONS

We conclude that the FFQ we have developed appears to be an acceptable tool for assessing the nutrient intakes in this population. Further studies for calibration of the FFQ collected from multicenters participating in the KoGES are needed.

SPONSORSHIP

This study was supported by the budget of the National Genome Research Institute, Korea National Institute of Health (2002-347-6111-221).

摘要

目的

评估为韩国基因组流行病学研究（KoGES）所开发的食物频率问卷（FFQ）的有效性和可靠性。

方法

FFQ每隔1年进行两次调查（研究开始时为首次FFQ（FFQ1），研究结束时为第二次FFQ（FFQ2）），并为那些前往健康检查中心的人在2002年12月至2004年5月的四个季节中，每个季节收集3天的饮食记录（DR）。在研究期结束时，我们收集了124名参与者的12天饮食记录。将饮食记录中的营养素摄入量与FFQ1和FFQ2进行比较。

结果

从FFQ1和FFQ2估算的能量和一些营养素的摄入量与饮食记录评估的结果不同。特别是，FFQ1和FFQ2中碳水化合物的摄入量高于饮食记录中的摄入量。在韩国人群中，FFQ2与12天饮食记录之间经去衰减、年龄、性别和能量摄入调整后的相关系数在0.23（维生素A）至0.64（碳水化合物）之间。所有营养素的中位数为0.39。当我们比较两种方法的营养素密度时，相关性相似。按四分位数对FFQ2和12天饮食记录评估的热量调整营养素摄入量进行联合分类，完全一致的范围从25.8%（维生素A）至39.5%（碳水化合物、铁）。除维生素A外，所有营养素中被归类到相差四分位数的受试者比例均小于7%。相隔1年的两次FFQ之间所有营养素摄入量相关性的中位数为0.45，营养素密度相关性的中位数为0.39。