无瘢痕胎儿愈合。治疗意义。
Scarless fetal healing. Therapeutic implications.
作者信息
Adzick N S, Longaker M T
机构信息
Fetal Treatment Program, University of California, San Francisco 94143-0570.
出版信息
Ann Surg. 1992 Jan;215(1):3-7. doi: 10.1097/00000658-199201000-00004.
Abstract
The purpose of this report is to call attention to the fetal wound healing process as a blueprint for ideal tissue repair. Wound healing in the fetus is fundamentally different from healing in the adult. Fetal tissue repair occurs rapidly and in the absence of scar formation. Because scarring and fibrosis dominate some diseases in every area of medicine, an understanding of fetal wound healing should help develop therapeutic strategies to avert the devastating consequences of excessive scar formation.
摘要
本报告的目的是提请关注胎儿伤口愈合过程，将其作为理想组织修复的蓝本。胎儿的伤口愈合与成人的愈合有着根本的不同。胎儿组织修复迅速且不会形成瘢痕。由于瘢痕形成和纤维化在医学各个领域的一些疾病中占主导地位，了解胎儿伤口愈合应有助于制定治疗策略，以避免过度瘢痕形成带来的毁灭性后果。
相似文献
1
Scarless fetal healing. Therapeutic implications.无瘢痕胎儿愈合。治疗意义。
Ann Surg. 1992 Jan;215(1):3-7. doi: 10.1097/00000658-199201000-00004.
2
Scar wars: implications of fetal wound healing for the pediatric burn patient.瘢痕之战：胎儿伤口愈合对小儿烧伤患者的影响
Pediatr Surg Int. 1997 Sep;12(7):484-9. doi: 10.1007/BF01258707.
3
Studies in fetal wound healing. V. A prolonged presence of hyaluronic acid characterizes fetal wound fluid.胎儿伤口愈合的研究。V. 透明质酸的长期存在是胎儿伤口液的特征。
Ann Surg. 1991 Apr;213(4):292-6. doi: 10.1097/00000658-199104000-00003.
4
Scarless wound healing in the mammalian fetus.哺乳动物胎儿的无瘢痕伤口愈合。
Surg Gynecol Obstet. 1992 May;174(5):441-51.
5
Scarless fetal skin wound healing update.无瘢痕胎儿皮肤伤口愈合的最新进展。
Birth Defects Res C Embryo Today. 2012 Sep;96(3):237-47. doi: 10.1002/bdrc.21018.
6
Scarless wound healing in the fetus: the role of the extracellular matrix.胎儿的无瘢痕伤口愈合：细胞外基质的作用。
Prog Clin Biol Res. 1991;365:177-92.
7
Cells, matrix, growth factors, and the surgeon. The biology of scarless fetal wound repair.细胞、基质、生长因子与外科医生。胎儿无瘢痕伤口修复的生物学机制。
Ann Surg. 1994 Jul;220(1):10-8. doi: 10.1097/00000658-199407000-00003.
8
Hyaluronan induces scarless repair in mouse limb organ culture.透明质酸在小鼠肢体器官培养中诱导无瘢痕修复。
J Pediatr Surg. 1998 Apr;33(4):564-7. doi: 10.1016/s0022-3468(98)90317-7.
9
Fetal cleft lip repair in lambs: histologic characteristics of the healing wound.绵羊胎儿唇裂修复：愈合伤口的组织学特征
Int J Oral Maxillofac Surg. 1993 Dec;22(6):371-4. doi: 10.1016/s0901-5027(05)80672-1.
10
Fetal scarless wound healing.胎儿无瘢痕伤口愈合。
J Otolaryngol. 1999 Oct;28(5):296-302.
引用本文的文献
1
Geometry-mediated bridging drives nonadhesive stripe wound healing.几何结构介导的桥连驱动非粘连条纹状伤口愈合。
Proc Natl Acad Sci U S A. 2023 May 2;120(18):e2221040120. doi: 10.1073/pnas.2221040120. Epub 2023 Apr 25.
2
Human fetal mesenchymal stem cells secretome promotes scarless diabetic wound healing through heat-shock protein family.人胎儿间充质干细胞分泌组通过热休克蛋白家族促进无瘢痕糖尿病伤口愈合。
Bioeng Transl Med. 2022 Jun 21;8(1):e10354. doi: 10.1002/btm2.10354. eCollection 2023 Jan.
3
A Systematic Review of the Effect of on Wound Healing.关于 对创伤愈合影响的系统评价。
Int J Environ Res Public Health. 2022 Mar 10;19(6):3266. doi: 10.3390/ijerph19063266.
4
The Effect of Amino Acids on Wound Healing: A Systematic Review and Meta-Analysis on Arginine and Glutamine.氨基酸对伤口愈合的影响：精氨酸和谷氨酰胺的系统评价和荟萃分析。
Nutrients. 2021 Jul 22;13(8):2498. doi: 10.3390/nu13082498.
5
Cx43 mediates changes in myofibroblast contraction and collagen release in human amniotic membrane defects after trauma.缝隙连接蛋白 43 介导创伤后人类羊膜缺陷中成纤维细胞收缩和胶原释放的变化。
Sci Rep. 2021 Aug 18;11(1):16975. doi: 10.1038/s41598-021-94767-4.
6
Industrial Development of Standardized Fetal Progenitor Cell Therapy for Tendon Regenerative Medicine: Preliminary Safety in Xenogeneic Transplantation.用于肌腱再生医学的标准化胎儿祖细胞疗法的产业发展：异种移植的初步安全性
Biomedicines. 2021 Apr 3;9(4):380. doi: 10.3390/biomedicines9040380.
7
Holistic Approach of Swiss Fetal Progenitor Cell Banking: Optimizing Safe and Sustainable Substrates for Regenerative Medicine and Biotechnology.瑞士胎儿祖细胞库的整体方法：为再生医学和生物技术优化安全且可持续的基质。
Front Bioeng Biotechnol. 2020 Oct 23;8:557758. doi: 10.3389/fbioe.2020.557758. eCollection 2020.
8
Regenerative Scar-Free Skin Wound Healing.再生无瘢痕皮肤创伤愈合。
Tissue Eng Part B Rev. 2019 Aug;25(4):294-311. doi: 10.1089/ten.TEB.2018.0350.
9
Wound Healing: A Cellular Perspective.创伤愈合：细胞视角。
Physiol Rev. 2019 Jan 1;99(1):665-706. doi: 10.1152/physrev.00067.2017.
10
Fibroblasts as a practical alternative to mesenchymal stem cells.成纤维细胞作为间充质干细胞的实用替代品。
J Transl Med. 2018 Jul 27;16(1):212. doi: 10.1186/s12967-018-1536-1.
本文引用的文献
1
Inflammation in the foetal and neonatal rat: the local reactions to skin burns.胎鼠和新生鼠的炎症：皮肤烧伤的局部反应。
J Pathol Bacteriol. 1960 Jul;80:73-82. doi: 10.1002/path.1700800109.
2
Healing of hyaluronic acid-enriched wounds: histological observations.富含透明质酸伤口的愈合：组织学观察
J Surg Res. 1983 Nov;35(5):410-6. doi: 10.1016/0022-4804(83)90030-6.
3
The physiology of high altitude.高原生理学。
Sci Am. 1970 Feb;222(2):52-62. doi: 10.1038/scientificamerican0270-52.
4
The neutrophilic leukocyte in wound repair a study with antineutrophil serum.伤口修复中的嗜中性白细胞：一项使用抗中性粒细胞血清的研究
J Clin Invest. 1972 Aug;51(8):2009-23. doi: 10.1172/JCI107007.
5
Beneficial effect of topical fibronectin in patients with keratoconjunctivitis sicca of Sjögren's syndrome.局部应用纤连蛋白对干燥综合征性角结膜炎患者的有益作用。
J Rheumatol. 1985 Jun;12(3):487-9.
6
Comparison of fetal, newborn, and adult wound healing by histologic, enzyme-histochemical, and hydroxyproline determinations.通过组织学、酶组织化学和羟脯氨酸测定比较胎儿、新生儿和成人的伤口愈合情况。
J Pediatr Surg. 1985 Aug;20(4):315-9. doi: 10.1016/s0022-3468(85)80210-4.
7
A model for the role of hyaluronic acid and fibrin in the early events during the inflammatory response and wound healing.透明质酸和纤维蛋白在炎症反应和伤口愈合早期事件中的作用模型。
J Theor Biol. 1986 Mar 21;119(2):219-34. doi: 10.1016/s0022-5193(86)80076-5.
8
Trophic effect of amniotic fluid on fetal gastrointestinal development.羊水对胎儿胃肠道发育的营养作用。
J Surg Res. 1986 Apr;40(4):291-6. doi: 10.1016/0022-4804(86)90189-7.
9
Diagnosis and management of fetal facial clefts.
Am J Obstet Gynecol. 1986 Aug;155(2):377-9. doi: 10.1016/0002-9378(86)90833-1.
10
Fetal surgery: a frontier for plastic surgery.胎儿外科手术：整形外科学的一个前沿领域。
Plast Reconstr Surg. 1986 Apr;77(4):645-7. doi: 10.1097/00006534-198604000-00024.
Zotero 插件