Chang Yoon Jung, Lee Jung Suk, Lee Chang Geol, Lee Won Sup, Lee Keun Seok, Bang Soo-Mee, Wang Xin Shelley, Mendoza Tito R, Cleeland Charles S, Yun Young Ho
Research Institute for National Cancer Control and Evaluation, National Cancer Center, Goyang, Gyeonggi, South Korea.
Support Care Cancer. 2007 Jul;15(7):891-6. doi: 10.1007/s00520-007-0219-x.
Fatigue is highly prevalent in cancer and greatly inferences with daily life. The goal of this study was to identify the most informative score in the Brief Fatigue Inventory and to define cut points for "mild," "moderate," and "severe" fatigue based on their relevance to quality of life (QOL).
We surveyed cancer patients at five hospitals in Korea with self-administrated questionnaires. The patients were older than 18 years, have a histological diagnosis of malignancy, gave informed consent to participate, and were able to understand the questionnaires. We analyzed 150 cancer patients who reported fatigue.
"Usual fatigue" was a sensitive and reliable indicator of fatigue severity and was defined as mild (1-3), moderate (4-7), or severe (8-10) because it had the strongest correlation with the functional interference, symptoms, depression, and QOL.
These cutpoints might be useful in clinical evaluation of fatigue in cancer. Our findings suggest a simple technique for the rapid screening of fatigue and for evaluating its impact on the symptoms and daily functioning of cancer patients.
疲劳在癌症患者中极为普遍，严重影响日常生活。本研究的目的是确定简明疲劳量表中最具信息量的评分，并根据其与生活质量（QOL）的相关性，定义“轻度”“中度”和“重度”疲劳的切点。
我们通过自填问卷对韩国五家医院的癌症患者进行了调查。患者年龄在18岁以上，经组织学诊断为恶性肿瘤，签署知情同意书并能够理解问卷内容。我们分析了150例报告有疲劳症状的癌症患者。
“日常疲劳”是疲劳严重程度的一个敏感且可靠的指标，根据其与功能干扰、症状、抑郁及生活质量的最强相关性，将其定义为轻度（1 - 3）、中度（4 - 7）或重度（8 - 10）。
这些切点可能有助于癌症患者疲劳的临床评估。我们的研究结果提示了一种简单的技术，可用于快速筛查疲劳，并评估其对癌症患者症状和日常功能的影响。
