Humphreys C T, Tallman B, Altmaier E M, Barnette V
Department of Psychological and Quantitative Foundations, The University of Iowa, Iowa City, IA 52242, USA.
Bone Marrow Transplant. 2007 Apr;39(8):491-6. doi: 10.1038/sj.bmt.1705613. Epub 2007 Feb 26.
Patients undergoing bone marrow transplantation (BMT) reported numerous sexual difficulties pretransplantation and at 1- and 3-years post transplantation. The most commonly reported problems pretransplant were a lack of sexual interest for men and self-perceived unattractiveness for women. At year 1, men reported more concern about physical attractiveness and increased problems with erection, ejaculation and orgasm. Women reported more sexual problems across all categories. At year 3, difficulties for men remained relatively consistent or decreased compared to year 1 with the exception of an increased concern about physical appearance. At year 3, women reported increased sexual interest; concerns about body appearance, vaginal dryness, painful intercourse and orgasm remained higher than at baseline, although all had decreased from year 1. Half of patients at all time points reported no discussion of sexuality with their health care provider. Baseline level of depression was significantly and positively related to sexual functioning at year 3 post transplant. These results suggest that sexual problems are significant for BMT survivors and that treatment of depression and health-care-provider education are possible interventional targets for improving sexual function and quality of life following BMT.
接受骨髓移植（BMT）的患者在移植前以及移植后1年和3年报告了许多性方面的困难。移植前最常报告的问题是男性缺乏性兴趣，女性自我感觉缺乏吸引力。在第1年，男性报告更担心身体吸引力，勃起、射精和性高潮问题增多。女性在所有类别中报告的性问题更多。在第3年，男性的困难与第1年相比相对保持稳定或有所减少，但对身体外观的担忧增加除外。在第3年，女性报告性兴趣增加；对身体外观、阴道干涩、性交疼痛和性高潮的担忧仍高于基线水平，尽管与第1年相比都有所下降。在所有时间点，一半的患者报告未与医护人员讨论过性问题。移植后第3年，抑郁的基线水平与性功能显著正相关。这些结果表明，性问题对BMT幸存者很重要，抑郁症治疗和医护人员教育可能是改善BMT后性功能和生活质量的干预目标。
