Altmaier E M, Gingrich R D, Fyfe M A
Division of Psychological and Quantitative Foundations, College of Education, University of Iowa, Iowa City.
Bone Marrow Transplant. 1991 Apr;7(4):311-6.
Very little systematic analysis exists on the psychological and emotional factors involved in bone marrow transplantation, either during or after treatment. However, recent published findings, contrary to earlier anecdotal and case study evidence, indicate that bone marrow transplant survivors appear to be functioning adequately on a variety of 'quality of life' variables. The purpose of the present study was to compare bone marrow transplant survivors to a matched sample of patients undergoing maintenance chemotherapy in four areas of function; physical health, including symptoms and physician visits; personal functioning, emphasizing ability to care for self; psychological functioning; and role functioning, including employment and sexual difficulties. Our data reveal that the bone marrow transplant patients were experiencing greater difficulties than the maintenance chemotherapy patients in several areas. For example, the bone marrow transplant patients had experienced greater disruption of vocational functioning and reported more sexual difficulties. However, in spite of more objective difficulties, bone marrow transplant patients, compared to maintenance chemotherapy patients, viewed themselves as equally healthy and reported similarly low levels of psychological distress. The findings are discussed in the context of necessary future research on bone marrow transplant survivors.
对于治疗期间或治疗后骨髓移植所涉及的心理和情感因素，几乎没有系统的分析。然而，最近发表的研究结果与早期的轶事和案例研究证据相反，表明骨髓移植幸存者在各种“生活质量”变量方面似乎功能良好。本研究的目的是在四个功能领域将骨髓移植幸存者与接受维持化疗的匹配患者样本进行比较；身体健康，包括症状和看医生的次数；个人功能，强调自我照顾能力；心理功能；以及角色功能，包括就业和性方面的困难。我们的数据显示，骨髓移植患者在几个方面比维持化疗患者面临更大的困难。例如，骨髓移植患者经历了更大的职业功能障碍，并且报告了更多的性方面的困难。然而，尽管存在更多客观困难，但与维持化疗患者相比，骨髓移植患者认为自己同样健康，并且报告的心理困扰水平同样较低。这些发现将在未来对骨髓移植幸存者进行必要研究的背景下进行讨论。
