Kummer Ann W, Lee Linda, Stutz Lindsay Schaadt, Maroney Adam, Brandt Jennifer Weidenbach
Speech Pathology Department, Cincinnati Children's Hospital Medical Center, and Professor of Clinical Pediatrics, University of Cincinnati Medical Center, Cincinnati, Ohio 45229-3039, USA.
Cleft Palate Craniofac J. 2007 Mar;44(2):175-81. doi: 10.1597/05-170.1.
The purpose of this study was to assess the oral-motor function of children with a history of cleft lip and palate, cleft palate only, velocardiofacial syndrome, and children with normal oral structures to determine if children with velocardiofacial syndrome have more apraxia characteristics than the other populations have.
The Apraxia Profile (Hickman, 1997) was administered to all participants in a prospective study.
The investigation was conducted at Cincinnati Children's Hospital Medical Center.
In this study, 10 children with cleft lip and palate, 10 with cleft palate only, 7 with velocardiofacial syndrome, and 47 with normal structures were tested.
This study revealed that when compared with children with normal structures, children with cleft lip and palate did not demonstrate significant apraxia characteristics, children with cleft palate only demonstrated some apraxia characteristics, and children with velocardiofacial syndrome demonstrated the most apraxia characteristics.
There appears to be a high prevalence of apraxia characteristics in the speech of patients with velocardiofacial syndrome. This information has implications for the type of treatment recommended. Further investigation is warranted with a larger patient population and a focus on the association of abnormal brain structure with apraxia in this population.
本研究旨在评估唇腭裂、单纯腭裂、腭心面综合征患儿以及口腔结构正常儿童的口腔运动功能，以确定腭心面综合征患儿是否比其他人群具有更多的失用症特征。
在一项前瞻性研究中，对所有参与者进行了失用症量表（希克曼，1997年）评估。
研究在辛辛那提儿童医院医疗中心进行。
本研究对10名唇腭裂患儿、10名单纯腭裂患儿、7名腭心面综合征患儿和47名口腔结构正常的儿童进行了测试。
本研究表明，与口腔结构正常的儿童相比，唇腭裂患儿未表现出明显的失用症特征，单纯腭裂患儿表现出一些失用症特征，而腭心面综合征患儿表现出的失用症特征最多。
腭心面综合征患者的言语中失用症特征似乎普遍存在。这一信息对推荐的治疗类型具有启示意义。有必要对更大的患者群体进行进一步研究，并关注该人群中异常脑结构与失用症的关联。
