Parker Emily D, Schmitz Kathryn H, Jacobs David R, Dengel Donald R, Schreiner Pamela J
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis 55454, USA.
Am J Public Health. 2007 Apr;97(4):703-9. doi: 10.2105/AJPH.2004.055889. Epub 2007 Feb 28.
We sought to examine the relation between physical activity and incident hypertension in young adults over 15 years of follow-up in the Coronary Artery Risk Development in Young Adults study.
A total of 3993 Black and White men and women aged 18 to 30 years were examined at baseline, and 2, 5, 7, 10, and 15 years later. Blood pressure and physical activity were measured at each exam. Hypertension was defined as systolic 140 mm Hg or higher, diastolic 90 mm Hg or higher, or antihypertensive medication use. Average physical activity and incident hypertension over 15 years of follow-up were analyzed.
There were 634 cases of incident hypertension over 15 years of follow-up. Those who were more versus less physically active experienced a reduced risk (hazard rate ratio = 0.83; 95% confidence interval = 0.73, 0.93) for incident hypertension, after adjustment for race, sex, age, education, and family history of high blood pressure.
Physical activity merits attention in the prevention of incident hypertension among young adults, particularly as they move into middle age.
在年轻人冠状动脉风险发展研究中，我们试图通过对年轻人进行超过15年的随访，来研究身体活动与高血压发病之间的关系。
共有3993名年龄在18至30岁之间的黑人和白人男性及女性在基线时接受了检查，并在2年、5年、7年、10年和15年后再次接受检查。每次检查时测量血压和身体活动情况。高血压定义为收缩压140毫米汞柱或更高、舒张压90毫米汞柱或更高，或正在使用抗高血压药物。分析了15年随访期间的平均身体活动情况和高血压发病情况。
在15年的随访期间有634例高血压发病病例。在对种族、性别、年龄、教育程度和高血压家族史进行调整后，身体活动较多与较少的人相比，高血压发病风险降低（风险率比=0.83；95%置信区间=0.73，0.93）。
身体活动在预防年轻人高血压发病方面值得关注，尤其是当他们步入中年时。
