Hadlock F P, Shah Y P, Kanon D J, Lindsey J V
Department of Radiology, Baylor College of Medicine, Houston, TX 77030.
Radiology. 1992 Feb;182(2):501-5. doi: 10.1148/radiology.182.2.1732970.
Because of recent challenges in the literature regarding the validity of the older crown-rump length (CRL) data developed with conventional static-image ultrasound scanners, the authors evaluated the relationship between CRL and menstrual age of fetuses in a population of 416 patients with good menstrual dates. By using a variety of commercially available transabdominal and transvaginal real-time ultrasound probes, the authors demonstrated that measurements can be made successfully for CRLs varying in size from 2 mm to 12 cm. Regression analysis of the data resulted in development of a new table for predicting menstrual age of fetuses on the basis of CRL measurements obtained between 5 and 18 weeks gestation. Although the magnitude of the raw residuals increased over time, the variability in predicting menstrual age was demonstrated to be relatively constant at +/- 8% (2 standard deviations) when expressed as a percentage of the predicted value. The accuracy in predicting menstrual age from CRL after 14 weeks was equivalent to but not better than conventional measurements such as biparietal diameter and femur length.
由于近期文献对使用传统静态图像超声扫描仪得出的旧的头臀长（CRL）数据的有效性提出了质疑，作者在416例月经日期记录良好的患者群体中评估了CRL与胎儿月经龄之间的关系。通过使用各种市售的经腹和经阴道实时超声探头，作者证明对于大小从2毫米至12厘米不等的CRL能够成功进行测量。对数据的回归分析得出了一个新表格，用于根据妊娠5至18周期间获得的CRL测量值预测胎儿的月经龄。尽管原始残差的幅度随时间增加，但当以预测值的百分比表示时，预测月经龄的变异性被证明相对恒定，为±8%（2个标准差）。14周后根据CRL预测月经龄的准确性与双顶径和股骨长度等传统测量方法相当，但并不优于它们。
