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一名感染人类免疫缺陷病毒儿童的慢性水痘带状疱疹:病例报告及文献复习

Chronic varicella zoster in a child infected with human immunodeficiency virus: case report and review of the literature.

作者信息

Leibovitz E, Kaul A, Rigaud M, Bebenroth D, Krasinski K, Borkowsky W

机构信息

Department of Pediatrics, New York University Medical Center, Bellevue Hospital, New York.

出版信息

Cutis. 1992 Jan;49(1):27-31.

PMID:1733656
Abstract

Chronic zoster represents an infrequent presentation of varicella zoster virus infection. It is observed with increased frequency in patients infected with human immunodeficiency virus, especially when their lymphocyte counts are depressed. We report a child infected with human immunodeficiency virus who showed a long-standing cutaneous zoster lesion and was treated for a prolonged period of time with acyclovir. The occurrence of resistance to acyclovir by varicella zoster virus was suspected based on the clinical picture. The clinical and laboratory features of this case and a review of the literature are presented.

摘要

慢性带状疱疹是水痘-带状疱疹病毒感染的一种罕见表现形式。在感染人类免疫缺陷病毒的患者中,其出现频率有所增加,尤其是当他们的淋巴细胞计数降低时。我们报告了一名感染人类免疫缺陷病毒的儿童,该儿童出现了长期的皮肤带状疱疹病变,并接受了长时间的阿昔洛韦治疗。根据临床表现怀疑水痘-带状疱疹病毒对阿昔洛韦产生了耐药性。本文介绍了该病例的临床和实验室特征,并对相关文献进行了综述。

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