美国医院中噬菌体模式特异性耐苯唑西林和苯唑西林临界耐药金黄色葡萄球菌：流行病学意义
Phage pattern-specific oxacillin-resistant and borderline oxacillin-resistant Staphylococcus aureus in U.S. hospitals: epidemiological significance.
作者信息
Zierdt C H, Hosein I K, Shively R, MacLowry J D
机构信息
Clinical Pathology Department, National Institutes of Health, Bethesda, Maryland 20892.
出版信息
J Clin Microbiol. 1992 Jan;30(1):252-4. doi: 10.1128/jcm.30.1.252-254.1992.
Abstract
For a 13-year period (1978 through 1990), oxacillin-resistant (MIC, greater than 4 micrograms/ml) Staphylococcus aureus (ORSA) strains were collected from Clinical Center (National Institutes of Health) patients and patients from five other U.S. hospitals. From Clinical Center patients, 251 of 253 isolates (99%) were bacteriophage typed as phage group III. Five other hospitals contributed 203 ORSA strains, of which 188 (93%) were group III. The group III ORSA strains predominantly included a characteristic core pattern of phages, 7/47/53/54/75/77. For the low-level (borderline) oxacillin-resistant strains (MIC, 2 to 4 micrograms/ml), amoxicillin-clavulanic acid combination (Augmentin) testing disclosed 62 hyper-beta-lactamase producers, of which 59 (95%) were of a separate, distinct S. aureus strain, with the phage pattern 92/94/96/292/D-11 (group V). Thus, ORSA and hyper-beta-lactamase producing S. aureus are distinct epidemic strains.
摘要
在13年期间（1978年至1990年），从临床中心（美国国立卫生研究院）的患者以及美国其他五家医院的患者中收集了耐苯唑西林（最低抑菌浓度大于4微克/毫升）的金黄色葡萄球菌（ORSA）菌株。在临床中心的患者中，253株分离菌中有251株（99%）被噬菌体分型为III组噬菌体。其他五家医院提供了203株ORSA菌株，其中188株（93%）为III组。III组ORSA菌株主要包括一组特征性的噬菌体核心模式，即7/47/53/54/75/77。对于低水平（临界）耐苯唑西林菌株（最低抑菌浓度为2至4微克/毫升），阿莫西林-克拉维酸联合制剂（奥格门汀）检测发现62株高产β-内酰胺酶菌株，其中59株（95%）属于一个单独的、独特的金黄色葡萄球菌菌株，其噬菌体模式为92/94/96/292/D-11（V组）。因此，ORSA和高产β-内酰胺酶的金黄色葡萄球菌是不同的流行菌株。
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本文引用的文献
1
NATURALLY OCCURING METHICILLIN-RESISTANT STAPHYLOCOCCI.天然存在的耐甲氧西林葡萄球菌
J Gen Microbiol. 1964 May;35:183-90. doi: 10.1099/00221287-35-2-183.
2
CHARACTERISTICS OF METHICILLIN-RESISTANT STAPHYLOCOCCI.耐甲氧西林葡萄球菌的特征
J Bacteriol. 1964 Apr;87(4):887-99. doi: 10.1128/jb.87.4.887-899.1964.
3
A multiple-syringe bacteriophage applicator.一种多注射器噬菌体涂抹器。
Am J Clin Pathol. 1960 Mar;33:233-7. doi: 10.1093/ajcp/33.3.233.
4
Methicillin-resistant staphylococci.耐甲氧西林葡萄球菌
J Clin Pathol. 1961 Jul;14(4):385-93. doi: 10.1136/jcp.14.4.385.
5
Multiply antibiotic-resistant Staphylococcus aureus: introduction, transmission, and evolution of nosocomial infection.多重耐药金黄色葡萄球菌：医院感染的介绍、传播与演变
Ann Intern Med. 1982 Sep;97(3):317-24. doi: 10.7326/0003-4819-97-3-317.
6
The emergence of methicillin-resistant Staphylococcus aureus infections in United States hospitals. Possible role of the house staff-patient transfer circuit.美国医院中耐甲氧西林金黄色葡萄球菌感染的出现。住院医生与患者转移循环的可能作用。
Ann Intern Med. 1982 Sep;97(3):297-308. doi: 10.7326/0003-4819-97-3-297.
7
Methicillin-resistant Staphylococcus aureus: microbiologic characteristics, antimicrobial susceptibilities, and assessment of virulence of an epidemic strain.耐甲氧西林金黄色葡萄球菌：一种流行菌株的微生物学特征、抗菌药敏性及毒力评估
J Infect Dis. 1981 Dec;144(6):575-82. doi: 10.1093/infdis/144.6.575.
8
Epidemiologic studies of an outbreak of nosocomial methicillin-resistant Staphylococcus aureus infections.医院内耐甲氧西林金黄色葡萄球菌感染暴发的流行病学研究
Infect Control. 1981 Mar-Apr;2(2):110-6. doi: 10.1017/s0195941700053881.
9
Computer analysis of Staphylococcus aureus phage typing data from 1957 to 1975, citing epidemiological trends and natural evolution within the phage typing system.对1957年至1975年金黄色葡萄球菌噬菌体分型数据的计算机分析，引用了噬菌体分型系统内的流行病学趋势和自然进化情况。
Appl Environ Microbiol. 1980 Mar;39(3):623-9. doi: 10.1128/aem.39.3.623-629.1980.
10
Changing staphylococci and staphylococcal infections. A ten-year study of bacteria and cases of bacteremia.
N Engl J Med. 1969 Sep 18;281(12):627-35. doi: 10.1056/NEJM196909182811201.
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