Shandera W X, Tormey M P, Blaser M J
Division of Field Services, Centers for Disease Control, Atlanta, Georgia.
Mt Sinai J Med. 1992 Jan;59(1):53-6.
During September 1980, an outbreak of bacteremic Campylobacter jejuni infection occurred in metropolitan Los Angeles. The outbreak was recognized when blood cultures obtained from 11 previously healthy persons with acute febrile illnesses (characterized in over 80% by fever, diarrhea, and headaches) were positive for C. jejuni. All recovered after an illness that lasted a mean of 8 days. A surveillance system failed to reveal a concomitant outbreak of gastroenteritis. Isolates had identical biochemical characteristics, susceptibility patterns to antimicrobial agents, and serotypes. Isolates from 2 patients were found to be susceptible to bactericidal activity of normal human serum. When bacteremic case-patients were matched with healthy controls, a significant association (p less than 0.05, odds ratio 10) between illness and consumption of processed turkey was established. Although turkey was not available for culture, and processing of turkey theoretically destroys Campylobacter, turkey carcasses are known to be heavily contaminated with the pathogen.
1980年9月期间，洛杉矶大都市地区爆发了空肠弯曲菌败血症感染疫情。当从11名先前健康的急性发热疾病患者（超过80%的症状为发热、腹泻和头痛）采集的血培养物中空肠弯曲菌呈阳性时，此次疫情得以确认。所有患者在平均持续8天的病程后均康复。一个监测系统未能发现同时爆发的肠胃炎疫情。分离菌株具有相同的生化特性、对抗菌药物的敏感性模式和血清型。发现2名患者的分离菌株对正常人血清的杀菌活性敏感。当将败血症病例患者与健康对照进行匹配时，发现疾病与食用加工火鸡之间存在显著关联（p<0.05，比值比为10）。尽管没有火鸡可供培养，且火鸡的加工理论上会破坏弯曲菌，但已知火鸡 carcasses 被这种病原体严重污染。 （注：这里carcasses未给出准确中文释义，推测可能是“屠体”之类的意思，原文可能有拼写错误，正确的或许是“carcasses”即“屠体”）
