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从微生物学到预防。

from microbiology to prevention.

作者信息

Facciolà A, Riso R, Avventuroso E, Visalli G, Delia S A, Laganà P

机构信息

Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.

出版信息

J Prev Med Hyg. 2017 Jun;58(2):E79-E92.

Abstract

In last years, Campylobacter spp has become one of the most important foodborne pathogens even in high-income countries. Particularly, in Europe, Campylobacteriosis is, since 2005, the foodborne disease most frequently notified and the second in USA, preceded by the infection due to Salmonella spp. Campylobacter spp is a commensal microorganism of the gastrointestinal tract of many wild animals (birds such as ducks and gulls), farm animals (cattle and pigs) and companion animals (such as dogs and cats) and it is responsible for zoonoses. The transmission occurs via the fecal-oral route through ingestion of contaminated food and water. The disease varied from a watery diarrhea to a severe inflammatory diarrhea with abdominal pain and fever and can be burdened by some complications. The main recognized sequelae are Guillain-Barré Syndrome (GBS), the Reactive Arthritis (REA) and irritable bowel syndrome (IBS). Recently, many cases of Campylobacter spp isolated from human infections, showed an important resistance to various antibiotics such as tetracyclines and fluoroquinolones. For these reasons, the prevention of this infection plays an essential role. Many preventive measures exist to limit the transmission of the pathogens and the subsequent disease such as the health surveillance, the vaccination of the poultry and the correct food hygiene throughout the entire production chain. A global surveillance of Campylobacteriosis is desirable and should include data from all countries, including notifications of cases and the microbiological data typing of strains isolated from both human and animal cases.

摘要

近年来,弯曲杆菌属已成为最重要的食源性病原体之一,即使在高收入国家也是如此。特别是在欧洲,自2005年以来,弯曲杆菌病是报告最频繁的食源性疾病,在美国则位居第二,仅次于沙门氏菌属感染。弯曲杆菌属是许多野生动物(如鸭子和海鸥等鸟类)、农场动物(牛和猪)以及伴侣动物(如狗和猫)胃肠道中的共生微生物,它可导致人畜共患病。传播通过粪口途径,经摄入受污染的食物和水发生。该病症状从水样腹泻到伴有腹痛和发热的严重炎症性腹泻不等,还可能伴有一些并发症。主要公认的后遗症是吉兰 - 巴雷综合征(GBS)、反应性关节炎(REA)和肠易激综合征(IBS)。最近,从人类感染中分离出的许多弯曲杆菌属菌株对多种抗生素(如四环素和氟喹诺酮类)表现出重要抗性。因此,预防这种感染起着至关重要的作用。存在许多预防措施来限制病原体的传播及随后的疾病,如健康监测、家禽疫苗接种以及整个生产链中的正确食品卫生。对弯曲杆菌病进行全球监测是可取的,应包括所有国家的数据,包括病例报告以及从人类和动物病例中分离出的菌株的微生物数据分型。

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本文引用的文献

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Compr Rev Food Sci Food Saf. 2004 Apr;3(2):105-116. doi: 10.1111/j.1541-4337.2004.tb00060.x.
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Update on the burden of Campylobacter in developing countries.发展中国家弯曲杆菌负担的最新情况。
Curr Opin Infect Dis. 2014 Oct;27(5):444-50. doi: 10.1097/QCO.0000000000000091.
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Preventing Campylobacter at the source: why is it so difficult?从源头预防弯曲菌:为何如此困难?
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