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荚膜组织胞浆菌作为一名来自孟加拉国的免疫功能正常的归国旅行者长期肺部疾病的病因。

Histoplasma capsulatum as a cause for prolonged pulmonary illness in an immunocompetent returning traveller from Bangladesh.

作者信息

Zafar Muhammad Rizwan, Whitfield Thomas, Zaidi Sabeen Khurshid, Weerakoon Sanjeewani, Paul Joel, Rautemaa-Richardson Riina

机构信息

North Manchester General Hospital, Delaunays Road, Crumpsall, Manchester, M8 5RB, United Kingdom.

The Royal Oldham Hospital, Rochdale Road, Oldham, OL1 2JH, United Kingdom.

出版信息

Med Mycol Case Rep. 2024 Apr 10;44:100647. doi: 10.1016/j.mmcr.2024.100647. eCollection 2024 Jun.

DOI:10.1016/j.mmcr.2024.100647
PMID:38634015
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11021948/
Abstract

Fungal infections can be challenging to diagnose in returning travellers due to their non-specific clinical manifestations and changing epidemiology. We present a case of progressive disseminated histoplasmosis in a returning traveller from Bangladesh. The patient had a progressive and prolonged respiratory illness necessitating mechanical ventilatory support. The clue to potential fungal aetiology was provided by serum fungal markers - 1-3-β-D-glucan and galactomannan. Diagnosis was eventually made using panfungal PCR on bronchioalveolar lavage fluid.

摘要

由于真菌感染的临床表现不具特异性且流行病学情况不断变化，因此对归国旅行者的真菌感染进行诊断可能具有挑战性。我们报告一例来自孟加拉国的归国旅行者发生进行性播散性组织胞浆菌病的病例。该患者患有进行性且持续时间较长的呼吸道疾病，需要机械通气支持。血清真菌标志物——1,3-β-D-葡聚糖和半乳甘露聚糖提示了潜在的真菌病因。最终通过对支气管肺泡灌洗液进行泛真菌PCR检测做出诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb60/11021948/b0dd87c9222c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb60/11021948/704020ac23f2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb60/11021948/b0dd87c9222c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb60/11021948/704020ac23f2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb60/11021948/b0dd87c9222c/gr2.jpg

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本文引用的文献

1
Infections in travellers returning to the UK: a retrospective analysis (2015-2020).返回英国的旅行者中的感染情况：一项回顾性分析（2015 - 2020年）
J Travel Med. 2023 Apr 5;30(2). doi: 10.1093/jtm/taad003.
2
Disseminated histoplasmosis in an immunocompetent patient with COVID-19 pneumonia.COVID-19 肺炎合并免疫功能正常的播散性组织胞浆菌病。
BMJ Case Rep. 2022 Jan 21;15(1):e247617. doi: 10.1136/bcr-2021-247617.
3
Occupational Histoplasmosis: Epidemiology and Prevention Measures.职业性组织胞浆菌病：流行病学与预防措施
J Fungi (Basel). 2021 Jun 26;7(7):510. doi: 10.3390/jof7070510.
4
Histoplasmosis Diagnosed in Europe and Israel: A Case Report and Systematic Review of the Literature from 2005 to 2020.欧洲和以色列诊断出的组织胞浆菌病：一例报告及2005年至2020年文献的系统综述
J Fungi (Basel). 2021 Jun 14;7(6):481. doi: 10.3390/jof7060481.
5
Histoplasmosis: An Emerging or Neglected Disease in Bangladesh? 
A Systematic Review.组织胞浆菌病：孟加拉国一种新出现的疾病还是被忽视的疾病？一项系统综述。
Oman Med J. 2020 Feb 16;35(1):e91. doi: 10.5001/omj.2020.09. eCollection 2020 Jan.
6
Histoplasmosis in an elderly polish tourist - a case report.老年波兰游客的组织胞浆菌病——一例报告。
BMC Pulm Med. 2019 Aug 14;19(1):150. doi: 10.1186/s12890-019-0914-7.
7
Clinical and epidemiological characterization of histoplasmosis cases in a nonendemic area, Connecticut, United States.美国康涅狄格州非流行地区组织胞浆菌病病例的临床和流行病学特征
Med Mycol. 2018 Oct 1;56(7):896-899. doi: 10.1093/mmy/myx120.
8
Burden of serious fungal infections in Bangladesh.孟加拉国严重真菌感染的负担。
Eur J Clin Microbiol Infect Dis. 2017 Jun;36(6):993-997. doi: 10.1007/s10096-017-2921-z. Epub 2017 Feb 4.
9
Histoplasmosis-associated cross-reactivity in the BioRad Platelia Aspergillus enzyme immunoassay.生物梅里埃公司的曲霉酶免疫测定法中组织胞浆菌病相关的交叉反应性。
Clin Vaccine Immunol. 2007 May;14(5):638-40. doi: 10.1128/CVI.00479-06. Epub 2007 Mar 7.
10
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Environ Health Perspect. 2005 May;113(5):585-9. doi: 10.1289/ehp.7484.