Kouam Simeon F, Yapna Diane B, Krohn Karsten, Ngadjui Bonaventure T, Ngoupayo Joseph, Choudhary Mohamed I, Schulz Barbara
Department of Chemistry, Higher Teachers' Training College, University of Yaounde 1, BP 47, Yaounde, Cameroon.
J Nat Prod. 2007 Apr;70(4):600-3. doi: 10.1021/np060556l. Epub 2007 Mar 13.
Three new prenylated anthranoids, harunmadagascarins C (1) and D (2) and kenganthranol D (3), together with three known compounds (4-6) were isolated from the leaves of Harungana madagascariensis. Their structures were assigned by spectroscopic methods and by comparison with literature data. In the three new natural products 1-3, one or two prenyl groups are incorporated in furan, pyran, or cyclohexane rings in four different modes of annulation. Compounds 2, 4, and 6 were strongly active against the Gram-positive Bacillus megaterium.
从马达加斯加哈伦加那树（Harungana madagascariensis）的叶子中分离出三种新的异戊烯基化蒽类化合物，即哈伦马岛素C（1）、哈伦马岛素D（2）和肯甘蒽醇D（3），以及三种已知化合物（4-6）。通过光谱方法并与文献数据比较确定了它们的结构。在这三种新的天然产物1-3中，一个或两个异戊烯基以四种不同的环合模式并入呋喃、吡喃或环己烷环中。化合物2、4和6对革兰氏阳性巨大芽孢杆菌具有很强的活性。
