Rea J D, Yarbrough D E, Leeth R R, Leath T D, Clements R H
Department of Surgery, Section of Gastrointestinal Surgery, University of Alabama at Birmingham, 1922 7th Avenue South KB 404, Birmingham, Alabama 35294-0016, USA.
Surg Endosc. 2007 Jul;21(7):1095-100. doi: 10.1007/s00464-007-9257-1. Epub 2007 Mar 13.
Obesity decreases health-related quality of life, but bariatric surgery improves it. This study evaluates the effect of laparoscopic Roux-en-Y gastric bypass, postoperative complications, and percentage of excess body weight loss on quality of life.
SF-36v.1 questionnaires were administered preoperative (n = 505), 1 year (n = 237) and 2 years (n = 106) following laparoscopic Roux-en-Y gastric bypass. Analysis was performed using Student's t-test and multiple logistic regression analysis. Complications were defined as requiring additional intervention or hospitalization. SF-36 responses were normalized to 1998 US norms.
Bariatric patients scored significantly lower on all scales compared to the normal population. Health-related quality of life notably improves after surgery. At 1 year, scores not only improved from baseline, but were higher than those of the non-obese reference population regardless of complications. Compared to patients at 2 years without complications, patients experiencing complications reported decreased scores, but scores remained higher than preoperative scores in five scales. At 1 and 2 years, < or = 50% excess body weight loss decreased scores; however, scores were significantly improved from baseline.
Health-related quality of life in bariatric patients is worse than in controls, but it improves 1 and 2 years after laparoscopic Roux-en-Y gastric bypass. Complications or < or = 50% excess body weight loss slightly decreases this improvement.
肥胖会降低与健康相关的生活质量,但减肥手术可改善这种状况。本研究评估了腹腔镜Roux-en-Y胃旁路手术的效果、术后并发症以及多余体重减轻百分比对生活质量的影响。
在腹腔镜Roux-en-Y胃旁路手术前(n = 505)、术后1年(n = 237)和2年(n = 106)发放SF-36v.1问卷。采用学生t检验和多元逻辑回归分析进行分析。并发症定义为需要额外干预或住院治疗。将SF-36的回答按照1998年美国标准进行标准化。
与正常人群相比,减肥手术患者在所有量表上的得分均显著较低。术后与健康相关的生活质量显著改善。在1年时,得分不仅较基线有所提高,而且无论有无并发症,均高于非肥胖参照人群。与2年时无并发症的患者相比,有并发症的患者得分较低,但在五个量表上的得分仍高于术前得分。在1年和2年时,多余体重减轻≤50%会降低得分;然而,得分较基线仍有显著改善。
减肥手术患者与健康相关的生活质量比对照组差,但在腹腔镜Roux-en-Y胃旁路手术后1年和2年有所改善。并发症或多余体重减轻≤50%会略微降低这种改善程度。