Gelecek Nihal, Teoman Nursen, Ozdirenc Mehtap, Pinar Lamia, Akan Pinar, Bediz Cem, Kozan Omer
School of Physical Therapy and Rehabilitation, Dokuz Eylul University, Izmir, Turkey.
Ann Nutr Metab. 2007;51(1):53-8. doi: 10.1159/000100821. Epub 2007 Mar 15.
Elevated plasma homocysteine (PH) levels have been identified as a risk factor for cardiovascular diseases. The aims of this study were to investigate the influences of submaximal acute aerobic exercise and aerobic training on PH levels and lipid profiles.
69 volunteer subjects (21.12 +/- 2.08 years) were randomized to three groups as acute, training and control groups. Examination and blood samples were collected before and immediately after exercise in the acute group and before and 6 weeks later in the training and control groups.
A significant increase in PH concentration was recorded immediately after aerobic exercise, compared with baseline values (p = 0.001). Although, in the training group, total cholesterol (p = 0.00) and LDL cholesterol (p = 0.001) decreased significantly after training, no significant changes in PH concentration, HDL cholesterol (p = 0.087) and triglyceride (p = 194) levels were found.
It can be said that the PH level increases following submaximal acute aerobic exercise, but does not alter after submaximal aerobic training due to training duration or intensity. Therefore, submaximal aerobic training decreases lipid profiles independent of the PH level.
血浆同型半胱氨酸（PH）水平升高已被确认为心血管疾病的一个风险因素。本研究的目的是调查次最大强度急性有氧运动和有氧训练对PH水平及血脂谱的影响。
69名志愿者（21.12±2.08岁）被随机分为三组，即急性组、训练组和对照组。急性组在运动前和运动后即刻采集检测样本和血样，训练组和对照组在运动前和6周后采集。
与基线值相比，有氧运动后即刻PH浓度显著升高（p = 0.001）。虽然训练组训练后总胆固醇（p = 0.00）和低密度脂蛋白胆固醇（p = 0.001）显著降低，但PH浓度、高密度脂蛋白胆固醇（p = 0.087）和甘油三酯（p = 194）水平未见显著变化。
可以说，次最大强度急性有氧运动后PH水平升高，但由于训练持续时间或强度，次最大强度有氧训练后PH水平未改变。因此，次最大强度有氧训练可降低血脂谱，与PH水平无关。
