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从炎性痤疮中分离出的痤疮丙酸杆菌菌株的抗菌药敏性。

Antimicrobial susceptibility of strains of Propionibacterium acnes isolated from inflammatory acne.

作者信息

Gübelin Walter, Martínez M Angélica, Molina M Teresa, Zapata Solange, Valenzuela M Eugenia

机构信息

Department of Dermatology, Faculty of Medicine, University of Chile.

出版信息

Rev Latinoam Microbiol. 2006 Jan-Mar;48(1):14-6.

Abstract

In the last decade, a significant increase in the antimicrobial resistance of clinical specimens of Propionibacterium acnes to first line antibiotics used for acne treatment, has been informed in Europe and in the USA. No information about strains isolated from Latin-American countries is available. The antimicrobial susceptibility of 53 strains of P. acnes isolated from skin specimens of inflammatory acne patients, at the clinical Hospital University of Chile was tested. All isolates were susceptible to penicillin, minocycline, and nadifloxacin. Erythromycin and clindamycin resistance was found in 3.8 and 1.9% isolates respectively. Resistance to lymecycline was observed in one isolate, which was intermediate to tetracycline and doxycycline.

摘要

在过去十年中,欧洲和美国均通报称,痤疮丙酸杆菌临床标本对用于痤疮治疗的一线抗生素的耐药性显著增加。目前尚无关于从拉丁美洲国家分离出的菌株的信息。对从智利大学临床医院炎症性痤疮患者皮肤标本中分离出的53株痤疮丙酸杆菌菌株进行了药敏试验。所有分离株对青霉素、米诺环素和纳地氟沙星敏感。分别有3.8%和1.9%的分离株对红霉素和克林霉素耐药。在一株分离株中观察到对赖甲环素耐药,该分离株对四环素和多西环素呈中介耐药。

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