Nishijima S, Kurokawa I, Kawabata S
Division of Dermatology, Kansai Medical University, Kori Branch Hospital, Osaka, Japan.
J Int Med Res. 1996 Nov-Dec;24(6):473-7. doi: 10.1177/030006059602400604.
The antimicrobial susceptibility of Propionibacterium acnes isolated before and after treatment of acne patients was measured. The four female and three male acne patients were treated with an oral acne medication, roxithromycin or minocycline, and/or a topical acne medication, nadifloxacin cream or clindamycin hydrochloride lotion for 1-8 weeks. The isolated strains were tested for their susceptibility to the antimicrobial action of: nadifloxacin, ofloxacin, erythromycin, clindamycin hydrochloride, tetracycline hydrochloride, minocycline, doxycycline, ampicillin, cephalexin and gentamycin. No resistant strains of P. acnes were observed.
测定了痤疮患者治疗前后分离出的痤疮丙酸杆菌的抗菌药敏性。4名女性和3名男性痤疮患者接受了口服痤疮药物（罗红霉素或米诺环素）和/或外用痤疮药物（那氟沙星乳膏或盐酸克林霉素洗剂）治疗1 - 8周。对分离出的菌株进行了对以下抗菌药物的药敏测试：那氟沙星、氧氟沙星、红霉素、盐酸克林霉素、盐酸四环素、米诺环素、多西环素、氨苄西林、头孢氨苄和庆大霉素。未观察到痤疮丙酸杆菌的耐药菌株。
