Hunter R H F, Cicinelli E, Einer-Jensen N
Institute for Reproductive Medicine, Hannover Veterinary University, Bünteweg 15, Hannover, Germany.
Acta Obstet Gynecol Scand. 2007;86(3):260-5. doi: 10.1080/00016340601155098.
This essay discusses the potential contribution of peritoneal fluid to the regulation of reproductive processes in female mammals. After noting the relatively high concentrations of diverse hormones in peritoneal fluid, and accepting that it bathes the surface of all the internal reproductive organs, peritoneal fluid is then proposed as a means of communication between the two ovaries. It could act to influence both the hierarchy of Graafian follicles and the rate and extent of development of a newly-formed corpus luteum. Cytokines in peritoneal fluid are considered in this context, as are the differing populations of leukocytes. Circumstantial evidence is offered for entry of peritoneal fluid into the Fallopian tubes, especially close to the time of ovulation, with the suggestion that such entry could modify the nature of endosalpingeal secretion and transudation. Thereafter, the spectrum of gonadal hormones in peritoneal fluid could be influencing uterine tissues in a local manner. Finally, reference is made to regional differences in the concentration of steroid hormones in the peritoneal fluid of women, likewise to regional differences in domestic animals.
本文探讨了腹膜液对雌性哺乳动物生殖过程调节的潜在作用。在注意到腹膜液中多种激素的浓度相对较高，并认识到它覆盖着所有内部生殖器官的表面之后，腹膜液被认为是两个卵巢之间的一种通讯方式。它可能会影响格拉夫卵泡的等级以及新形成的黄体的发育速度和程度。在此背景下，腹膜液中的细胞因子以及不同类型的白细胞都被纳入了考虑范围。有间接证据表明腹膜液会进入输卵管，尤其是在排卵前后，这表明这种进入可能会改变输卵管内膜分泌和渗出的性质。此后，腹膜液中的性腺激素谱可能会以局部方式影响子宫组织。最后，文中提到了女性腹膜液中类固醇激素浓度的区域差异，家畜腹膜液中的区域差异亦是如此。
