Hederstierna Christina, Hultcrantz Malou, Collins Aila, Rosenhall Ulf
Department of Audiology, Karolinska University Hospital, Stockholm, Sweden.
Acta Otolaryngol. 2007 Feb;127(2):149-55. doi: 10.1080/00016480600794446.
Hormone replacement therapy (HRT) may have a protective effect on hearing impairment in postmenopausal women. New guidelines for classification of audiometric configuration in age-related hearing loss are suggested.
To describe prevalence of hearing loss and audiometric configuration in a group of middle-aged women with respect to menopausal stage and HRT.
A total of 143 women around menopause were sampled through the Swedish population register. The mean hearing threshold levels were compared according to menopausal status. The audiograms in the 57 women with hearing loss were classified according to audiometric configuration.
In all, 57 women (40%) had any kind of hearing loss; 42 had very minute hearing loss; 15 had a 4FA (average of thresholds at 0.5, 1, 2, and 4 kHz) of at least 20-39 dB HL in at least one ear. Two of these had a 4FA of 40-69 dB HL in at least one ear. The most common configurations were: gently sloping (47%), steeply sloping (14%), and high-frequency U-shaped (14%). The postmenopausal women who were not on HRT had poorer hearing mainly at 2 and 3 kHz, compared with pre- and perimenopausal women, and postmenopausal women on HRT.
激素替代疗法(HRT)可能对绝经后女性的听力障碍具有保护作用。建议采用年龄相关性听力损失听力学构型分类新指南。
描述一组中年女性在绝经阶段和激素替代疗法方面的听力损失患病率及听力学构型。
通过瑞典人口登记册对总共143名绝经前后女性进行抽样。根据绝经状态比较平均听力阈值水平。对57名听力损失女性的听力图按照听力学构型进行分类。
总共57名女性(40%)有任何类型的听力损失;42名有非常轻微的听力损失;15名女性至少一只耳朵的4FA(0.5、1、2和4kHz阈值的平均值)至少为20 - 39dB HL。其中两名女性至少一只耳朵的4FA为40 - 69dB HL。最常见的构型为:轻度斜坡形(47%)、重度斜坡形(14%)和高频U形(14%)。与绝经前、围绝经期女性以及接受激素替代疗法的绝经后女性相比,未接受激素替代疗法的绝经后女性主要在2kHz和3kHz处听力较差。