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[帕金森病中的电刺激(ECT)]

[Electric stimulation (ECT) in Parkinson disease].

作者信息

Dam H, Pakkenberg H, Bolwig T G

机构信息

Rigshospitalet, psykiatrisk afdeling O, København.

出版信息

Ugeskr Laeger. 1992 Jan 20;154(4):183-7.

PMID:1736441
Abstract

A case report and a review of the literature concerning electroconvulsive therapy (ECT) in the treatment of Parkinson's disease with special reference to the therapy of "on-off" phenomena is given. The first report of positive effect appeared in 1959 and, with a single exception, all published articles on this topic point to a positive outcome of ECT. There seems to be a specific anti-Parkinsonian effect alongside the well-known effect on various psychotic conditions. ECT thus must be considered a valuable intervention when drug therapy is insufficient, when prolonged medication leads to decreased efficacy, or when patients develop neuro-psychiatric manifestations. A short review of the pathophysiological mechanisms which may underly the effect of ECT in Parkinson's disease is given.

摘要

本文给出了一例病例报告,并对有关电休克疗法(ECT)治疗帕金森病,特别是治疗“开-关”现象的文献进行了综述。关于ECT产生积极效果的首次报告出现在1959年,并且除了一篇文章外,所有关于该主题的已发表文章均指出ECT有积极疗效。除了对各种精神疾病的众所周知的作用外,似乎还存在一种特定的抗帕金森病作用。因此,当药物治疗不足、长期用药导致疗效降低或患者出现神经精神表现时,ECT必须被视为一种有价值的干预措施。本文还对可能是ECT在帕金森病中发挥作用基础的病理生理机制进行了简要综述。

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