Yu Tao, Gao Qing-hong, Wang Xiao-yi, Wen Yu-ming, Wang Chang-mei, Zhang Yong
Dept. of Head and Neck Oncology Surgery, West China College of Stomatology, Sichuan University, Chengdu 610041, China.
Hua Xi Kou Qiang Yi Xue Za Zhi. 2007 Feb;25(1):64-6.
To assess the clinical and histological features and therapeutic efficacy of 30 cases of malignant sublingual salivary gland tumors.
The clinicopathologic data of 30 patients with malignant sublingual salivary gland tumor were obtained from West China Hospital of Stomatology, Sichuan University from 1955 to 2005.
There were 18 male and 12 female, and the average age of patients was 50.6 years old. Seventeen cases were adenoid cystic carcinoma, accounting for 56.7%. There were 17 cases clinically staged as III, accounting for 56.7%. Distant metastasis and tumor recurrence were the main death reasons. The overall local recurrence rate was 30.0%, and distant metastasis rate was 26.7%.
Sublingual gland malignant tumors are rare and most of them are adenoid cystic carcinoma. Surgery is the main treatment option. The resection of the tumor accompanying with the neck dissection is the key method to achieve good therapeutic effect. The postoperative radiotherapy and chemotherapy should be adjuvant.
评估30例舌下腺恶性肿瘤的临床及组织学特征与治疗效果。
收集1955年至2005年四川大学华西口腔医院收治的30例舌下腺恶性肿瘤患者的临床病理资料。
男性18例，女性12例，患者平均年龄50.6岁。腺样囊性癌17例，占56.7%。临床分期为Ⅲ期者17例，占56.7%。远处转移和肿瘤复发是主要死亡原因。总体局部复发率为30.0%，远处转移率为26.7%。
舌下腺恶性肿瘤罕见，多数为腺样囊性癌。手术是主要治疗手段。肿瘤切除联合颈部淋巴结清扫是取得良好治疗效果的关键方法。术后应辅以放疗和化疗。
