Durgam Lavan K, Oroszi Terry L
Department of Pharmacology and Toxicology, Boonshoft School of Medicine, Wright State University, Fairborn, OH, United States.
Front Drug Deliv. 2025 May 30;5:1556426. doi: 10.3389/fddev.2025.1556426. eCollection 2025.
Medical science stands on the brink of transformation thanks to nanotechnology's fast-paced development, which promises major advancements. Working with materials at the nanoscale within a 1-100 nm range allows scientists to tap into special physicochemical characteristics that open up new possibilities in diagnostics, drug delivery, and regenerative medicine. The review explores nanotechnology's revolutionary effects on healthcare by highlighting its roles in medical imaging applications and diagnostic procedures, drug delivery systems, tissue engineering, and vaccine development. The design principles of nanomaterials, which encompass synthesis methods alongside functionalization and characterization techniques, are presented here. This review analyzes the impact of artificial intelligence in nanomedicine alongside the enduring effects of nanomaterials and related ethical and safety issues. The review further combines multiple study findings to offer a thorough overview of nanotechnology's medical applications while suggesting research and clinical translation paths.
由于纳米技术的快速发展,医学正处于变革的边缘,有望取得重大进展。在1-100纳米范围内处理纳米级材料,使科学家能够利用特殊的物理化学特性,为诊断、药物递送和再生医学开辟新的可能性。本综述通过强调纳米技术在医学成像应用、诊断程序、药物递送系统、组织工程和疫苗开发中的作用,探讨其对医疗保健的革命性影响。本文介绍了纳米材料的设计原则,包括合成方法以及功能化和表征技术。本综述分析了人工智能在纳米医学中的影响,以及纳米材料的持久影响和相关的伦理与安全问题。该综述进一步结合多项研究结果,全面概述纳米技术的医学应用,同时提出研究和临床转化途径。