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肾积水程度会影响体外冲击波碎石术治疗输尿管下段结石的成功率吗?

Does degree of hydronephrosis affect success of extracorporeal shock wave lithotripsy for distal ureteral stones?

作者信息

el-Assmy Ahmed, el-Nahas Ahmed R, Youssef Ramy F, el-Hefnawy Ahmed S, Sheir Khaled Z

机构信息

Urology and Nephrology Center, Mansoura University, Mansoura, Egypt.

出版信息

Urology. 2007 Mar;69(3):431-5. doi: 10.1016/j.urology.2006.11.010.

Abstract

OBJECTIVES

To investigate the relation between the degree of stone-induced hydronephrosis and the outcome of shock wave lithotripsy in patients with distal ureter stones.

METHODS

A total of 215 patients with a solitary distal ureter stone with or without hydronephrosis were treated with shock wave lithotripsy. The degree of hydronephrosis was determined by renal ultrasonography. The patients were divided into four groups according to the degree of stone-induced hydronephrosis. Group 0 (44.2%) had no urinary system dilation, group 1 (32.5%) had mild dilation, group 2 (16.3%) had moderate dilation, and group 3 (7%) had severe dilation. The patients were treated with the Dornier MFL 5000 lithotripter. The results were compared in terms of the stone-free rates, number of shock waves, number of sessions, incidence of complications, number of secondary interventions, and time to stone clearance.

RESULTS

The mean stone size was 11.2 +/- 2.5 mm. In the hydronephrotic group, the stone-free rate was 74% compared with 83% in patients without hydronephrosis (P = 0.27). The mean time to stone clearance was 16.3 +/- 9.2 days. The differences among the four groups in terms of stone size and treatment outcome were not significant. However, the presence of hydronephrosis was significantly associated with repeat treatment (2.2 versus 1.6, P <0.001) and prolonged clearance time (18.7 versus 15.4 days, P <0.001).

CONCLUSIONS

The results of our study have shown that in patients with solitary distal ureter stones, the degree of hydronephrosis caused by the stone does not affect the overall treatment success with shock wave lithotripsy. However, stones in obstructed systems tended to require repeat treatment and prolonged time for stone clearance.

摘要

目的

探讨输尿管下段结石患者结石所致肾积水程度与冲击波碎石治疗效果之间的关系。

方法

总共215例患有单个输尿管下段结石伴或不伴肾积水的患者接受了冲击波碎石治疗。通过肾脏超声检查确定肾积水程度。根据结石所致肾积水程度将患者分为四组。0组(44.2%)无泌尿系统扩张,1组(32.5%)有轻度扩张,2组(16.3%)有中度扩张,3组(7%)有重度扩张。患者使用多尼尔MFL 5000碎石机进行治疗。比较了结石清除率、冲击波次数、治疗次数、并发症发生率、二次干预次数和结石清除时间等结果。

结果

平均结石大小为11.2±2.5毫米。在肾积水组中,结石清除率为74%,而无肾积水患者为83%(P = 0.27)。平均结石清除时间为16.3±9.2天。四组在结石大小和治疗效果方面的差异不显著。然而,肾积水的存在与重复治疗(2.2比1.6,P<0.001)和清除时间延长(18.7天比15.4天,P<0.001)显著相关。

结论

我们的研究结果表明,对于单个输尿管下段结石患者,结石所致肾积水程度不影响冲击波碎石的总体治疗成功率。然而,梗阻系统中的结石往往需要重复治疗且结石清除时间延长。

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