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影响使用Piezolith 3000型体外冲击波碎石术治疗孤立性输尿管结石失败的因素。

Factors influencing the failure of extracorporeal shock wave lithotripsy with Piezolith 3000 in the management of solitary ureteral stone.

作者信息

Hwang Insang, Jung Seung-Il, Kim Kwang Ho, Hwang Eu Chang, Yu Ho Song, Kim Sun-Ouck, Kang Taek Won, Kwon Dong Deuk, Park Kwangsung

机构信息

Department of Urology, Chonnam National University, 42, Jebongno, Gwangju, Donggu, 501-757, Republic of Korea.

出版信息

Urolithiasis. 2014 Jun;42(3):263-7. doi: 10.1007/s00240-014-0641-8. Epub 2014 Feb 5.

Abstract

Studies of predictive factors of extracorporeal shockwave lithotripsy (ESWL) failure in patients with ureteral stones have not yielded results sufficient to prevent ESWL failure. The present study investigated patients with ureteral stone and analyzed the predictive factors of ESWL failure. Ninety patients with ureteral stone treated from January 2006 to June 2012 using ESWL for ureteral stone were enrolled. Patient's demographic data including age, gender, body mass index (BMI), symptoms and calculous characteristics including location, size, episode and the grade of hydronephrosis were recorded. Statistical results were performed using univariate and multivariate analyses for the predictive factors of ESWL failure. In univariate analysis, calculous location, size, and grade of hydronephrosis between two groups displayed significant differences (p < 0.05). The predictive factors of ESWL failure were BMI >25 kg/m(2) [Odds ratio (OR) = 3.5, 95% confidence interval (CI) 1.1-11.0], calculous size ≥ 1 cm (OR = 10.5, 95% CI 3.0-36.2), calculous location (mid-ureter; OR = 8.49, 95% CI 1.5-45.7) and severe grade of hydronephrosis (OR = 12.3, 95% CI 1.9-79.5). In conclusions, ESWL failure can be predicted in cases of obesity, calculous size exceeding 1 cm, mid-ureteral stone and severe hydronephrosis. When we consider calculous management in patients with these risk factors, initial surgical approach is recommended instead of ESWL.

摘要

关于输尿管结石患者体外冲击波碎石术(ESWL)失败预测因素的研究尚未得出足以预防ESWL失败的结果。本研究对输尿管结石患者进行调查,并分析ESWL失败的预测因素。纳入了2006年1月至2012年6月间采用ESWL治疗输尿管结石的90例患者。记录患者的人口统计学数据,包括年龄、性别、体重指数(BMI)、症状以及结石特征,包括位置、大小、发作情况和肾积水程度。对ESWL失败的预测因素进行单因素和多因素分析以得出统计结果。单因素分析显示,两组之间的结石位置、大小和肾积水程度存在显著差异(p<0.05)。ESWL失败的预测因素为BMI>25 kg/m²[比值比(OR)=3.5,95%置信区间(CI)1.1 - 11.0]、结石大小≥1 cm(OR = 10.5,95%CI 3.0 - 36.2)、结石位置(输尿管中段;OR = 8.49,95%CI 1.5 - 45.7)和重度肾积水(OR = 12.3,95%CI 1.9 - 79.5)。结论是,肥胖、结石大小超过1 cm、输尿管中段结石和重度肾积水的情况下可预测ESWL失败。当我们考虑对有这些危险因素的患者进行结石处理时,建议首选手术方法而非ESWL。

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