Wilson J A, Pryde A, Allan P L, Maran A G
Department of Otolaryngology, Royal Infirmary, Edinburgh, Scotland.
Otolaryngol Head Neck Surg. 1992 Feb;106(2):163-8.
The aim of the study was to determine the manometric patterns in dysphagic patients with radiologic evidence of upper esophageal sphincter (UES) dysfunction. Nineteen patients with radiographic abnormalities of the UES underwent measurement of several parameters of UES tonic pressure and pharyngoesophageal water swallow dynamics. At least two UES tonic pressures were elevated in six subjects, compared with a control group of 67 healthy volunteers. No patients had UES achalasia. The cricopharyngeal impression in the remaining patients may represent muscular hypertrophy or deficiency of UES opening, despite manometric relaxation, but its relationship to the patient's symptoms remains unknown. Cricopharyngeal myotomy appears to be a reasonable treatment for patients with manometric UES hypertonicity.
本研究的目的是确定有食管上括约肌(UES)功能障碍影像学证据的吞咽困难患者的测压模式。19例UES影像学异常的患者接受了UES静息压及咽食管吞水动力学若干参数的测量。与67名健康志愿者组成的对照组相比,6名受试者的至少两项UES静息压升高。没有患者存在UES失弛缓症。其余患者的环咽肌压迹可能代表肌肉肥大或UES开放不足,尽管测压显示有松弛,但它与患者症状的关系仍不清楚。对于测压显示UES张力亢进的患者,环咽肌切开术似乎是一种合理的治疗方法。