酵母中的基因相互作用：稳健性是否正在崩溃？ - Suppr

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Genetic interactions in yeast: is robustness going bust?

作者信息

Kupiec Martin, Sharan Roded, Ruppin Eytan

机构信息

Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Tel Aviv, Israel.

出版信息

Mol Syst Biol. 2007;3:97. doi: 10.1038/msb4100146. Epub 2007 Mar 27.

DOI:10.1038/msb4100146

PMID:17389877

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1847952/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4134/1847952/11b50750bd74/msb4100146-f1.jpg

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Global analysis of gene function in yeast by quantitative phenotypic profiling.

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Direct evolution of genetic robustness in microRNA.

Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6593-8. doi: 10.1073/pnas.0510600103. Epub 2006 Apr 11.

Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile.

Cell. 2005 Nov 4;123(3):507-19. doi: 10.1016/j.cell.2005.08.031.

Transcription control reprogramming in genetic backup circuits.

Nat Genet. 2005 Mar;37(3):295-9. doi: 10.1038/ng1523. Epub 2005 Feb 20.

Structure and evolution of protein interaction networks: a statistical model for link dynamics and gene duplications.

BMC Evol Biol. 2004 Nov 27;4:51. doi: 10.1186/1471-2148-4-51.

Can genes be truly redundant?

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相似文献

Genetic interactions in yeast: is robustness going bust?

Mol Syst Biol. 2007;3:97. doi: 10.1038/msb4100146. Epub 2007 Mar 27.

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Modular epistasis and the compensatory evolution of gene deletion mutants.

PLoS Genet. 2019 Feb 15;15(2):e1007958. doi: 10.1371/journal.pgen.1007958. eCollection 2019 Feb.

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引用本文的文献

Neighbor overlap is enriched in the yeast interaction network: analysis and implications.

PLoS One. 2012;7(6):e39662. doi: 10.1371/journal.pone.0039662. Epub 2012 Jun 26.

Identifying neighborhoods of coordinated gene expression and metabolite profiles.

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Dispensability of Escherichia coli's latent pathways.

Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3124-9. doi: 10.1073/pnas.1009772108. Epub 2011 Feb 7.

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HFSP J. 2009 Oct;3(5):290-306. doi: 10.2976/1.3167215. Epub 2009 Oct 19.

Improved network performance via antagonism: From synthetic rescues to multi-drug combinations.

Bioessays. 2010 Mar;32(3):236-245. doi: 10.1002/bies.200900128.

本文引用的文献

Backup without redundancy: genetic interactions reveal the cost of duplicate gene loss.

Mol Syst Biol. 2007;3:86. doi: 10.1038/msb4100127. Epub 2007 Mar 27.

Plasticity of genetic interactions in metabolic networks of yeast.

Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2307-12. doi: 10.1073/pnas.0607153104. Epub 2007 Feb 6.

Multiple knockout analysis of genetic robustness in the yeast metabolic network.

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Nat Genet. 2005 Mar;37(3):295-9. doi: 10.1038/ng1523. Epub 2005 Feb 20.

Structure and evolution of protein interaction networks: a statistical model for link dynamics and gene duplications.

BMC Evol Biol. 2004 Nov 27;4:51. doi: 10.1186/1471-2148-4-51.

Can genes be truly redundant?

Curr Biol. 1992 Oct;2(10):553-4. doi: 10.1016/0960-9822(92)90036-a.

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Nature. 2004 Jun 10;429(6992):661-4. doi: 10.1038/nature02636.