McCann Theresa M, Simpson Kerry E, Shaw Darren J, Butt Jennifer A, Gunn-Moore Danielle A
Division of Veterinary Clinical Sciences, Royal (Dick) School of Veterinary Studies, University of Edinburgh Hospital for Small Animals, Easter Bush Veterinary Centre, Roslin, Midlothian EH25 9RG, UK.
J Feline Med Surg. 2007 Aug;9(4):289-99. doi: 10.1016/j.jfms.2007.02.001. Epub 2007 Mar 27.
Prevalence and risk factors for the development of diabetes mellitus (DM) in cats in the United Kingdom have not previously been reported. The prevalence of DM was evaluated in a large insured population and was found to be 1 in 230 cats. In this insured cat population Burmese cats were 3.7 times more likely to develop DM than non-pedigree cats. A convenience-sampling questionnaire-based study was used in order to identify putative risk factors for the development of DM. The univariate risk factor analysis identified being male, neutered, inactive, weighing >or=5 kg and having a history of corticosteroid treatment as significant risk factors for the development of DM in these cats. In addition, male cats treated with megestrol acetate had a significantly increased risk of developing DM compared to females. In contrast, there was no difference in DM occurrence between male and female Burmese cats. A multivariate classification tree-based model on the questionnaire data looking for interactions between risk factors, identified gender as the most important overall risk factor for the development of DM with low physical activity being the next most important risk factor for female cats and breed the next most important for male cats.
英国猫糖尿病（DM）的患病率及发病风险因素此前尚无报道。在一大群参保猫中评估了DM的患病率，发现每230只猫中有1只患病。在这群参保猫中，缅甸猫患DM的可能性是非纯种猫的3.7倍。为了确定DM发病的假定风险因素，采用了一项基于方便抽样问卷调查的研究。单因素风险因素分析确定，雄性、绝育、不活跃、体重≥5 kg以及有皮质类固醇治疗史是这些猫患DM的显著风险因素。此外，与雌性相比，接受醋酸甲地孕酮治疗的雄性猫患DM的风险显著增加。相比之下，雄性和雌性缅甸猫患DM的情况没有差异。基于问卷数据构建的多变量分类树模型用于寻找风险因素之间的相互作用，结果确定性别是DM发病最重要的总体风险因素，低体力活动是雌性猫第二重要的风险因素，品种是雄性猫第二重要的风险因素。
