Rand J S, Bobbermien L M, Hendrikz J K, Copland M
School of Veterinary Science, University of Queensland, South Australia.
Aust Vet J. 1997 Jun;75(6):402-5. doi: 10.1111/j.1751-0813.1997.tb14340.x.
To determine if Burmese cats in Queensland have an increased risk of diabetes mellitus.
A retrospective study of diabetic and nondiabetic cats that had blood submitted to a veterinary clinical laboratory over a 22 month study period.
4402 cats
Cats were considered diabetic if blood glucose concentration was > 11 mmol/L and fructosamine was > 406 mumol/L or hydroxybutyrate was > 1 mmol/L. Cats were grouped into Burmese and non-Burmese. Adjusted odds ratios of diabetes were calculated for breed, gender and age group amongst cats with blood glucose > 11 mmol/L.
Burmese cats comprised 20% of 45 diabetic cats of known breed, which was higher (P < 0.001) than among the normoglycemic reference population of 2203 cats (7% Burmese). There were more females among the diabetic Burmese (62%), but this did not differ (P > 0.05) from the Burmese reference population (45% females). In contrast, males seemed to predominate among diabetic non-Burmese (63%), although this also did not differ (P > 0.05) from the reference population (55%) of from diabetic Burmese (38% males). The majority (90%) of diabetic cats were older than 6 years, irrespective of breed (median age 12 years, interquartile range 10 to 13 years). This was higher (chi(2) = 8.13, P < 0.005) than among the normoglycaemic reference population, where 69% were older than 6 years.
Burmese cats were significantly over represented among cats with diabetes mellitus. Irrespective of breed, the risk of diabetes in the study population increased with age.
确定昆士兰州的缅甸猫患糖尿病的风险是否增加。
对在22个月研究期间向兽医临床实验室提交血液样本的糖尿病猫和非糖尿病猫进行回顾性研究。
4402只猫
若血糖浓度>11 mmol/L且果糖胺>406 μmol/L或β-羟丁酸>1 mmol/L，则猫被视为患有糖尿病。猫被分为缅甸猫和非缅甸猫。对血糖>11 mmol/L的猫，计算品种、性别和年龄组的糖尿病调整比值比。
在已知品种的45只糖尿病猫中，缅甸猫占20%，这一比例高于2203只血糖正常的对照猫群体（7%为缅甸猫）（P<0.001）。糖尿病缅甸猫中雌性更多（62%），但与缅甸猫对照群体（45%为雌性）相比无差异（P>0.05）。相比之下，糖尿病非缅甸猫中雄性似乎占主导（63%），不过与对照群体（55%）或糖尿病缅甸猫（38%为雄性）相比也无差异（P>0.05）。大多数（90%）糖尿病猫年龄大于6岁，与品种无关（中位年龄12岁，四分位间距10至13岁）。这一比例高于血糖正常的对照群体（χ²=8.13，P<0.005），对照群体中69%的猫年龄大于6岁。
缅甸猫在糖尿病猫中所占比例显著过高。无论品种如何，研究群体中患糖尿病的风险随年龄增加。
