Graeter Stefan V, Huang Jinghuan, Perschmann Nadine, López-García Mónica, Kessler Horst, Ding Jiandong, Spatz Joachim P
Max-Planck-Institute for Metals Research, Department of New Materials and Biosystems, D-70569 Stuttgart, Germany.
Nano Lett. 2007 May;7(5):1413-8. doi: 10.1021/nl070098g. Epub 2007 Mar 30.
We present herein an innovative technique for decorating soft polymer surfaces with metallic nanostructures fabricated by diblock copolymer micelle nanolithography. Thus far, such nanolithography has been limited to plasma-resistant inorganic substrates such as glass. Our new development is based on the transfer of nanopatterns from glass to soft substrates. Special emphasis is given to hydrogel surfaces with respect to their properties for tailoring cell adhesion. Besides planar surfaces, periodic gold nanopatterns on curved surfaces have been fabricated, as demonstrated on the interior surface of a tubelike hydrogel, which potentially mimic situations of vessels in vivo.
我们在此展示了一种创新技术，可通过双嵌段共聚物胶束纳米光刻法在软聚合物表面装饰金属纳米结构。迄今为止，这种纳米光刻技术仅限于玻璃等抗等离子体无机基板。我们的新进展基于将纳米图案从玻璃转移到软基板上。特别强调了水凝胶表面在定制细胞黏附特性方面的作用。除了平面表面，还在弯曲表面上制造了周期性金纳米图案，如在管状水凝胶的内表面所示，这可能模拟体内血管的情况。
