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喉咽反流的趋势:一项英国耳鼻喉科调查。

Trends in laryngopharyngeal reflux: a British ENT survey.

作者信息

Karkos P D, Benton J, Leong S C, Karkanevatos A, Badran K, Srinivasan V R, Temple R H, Issing W J

机构信息

Department of Otolaryngology, Arrowe Park Hospital, Wirral, UK.

出版信息

Eur Arch Otorhinolaryngol. 2007 May;264(5):513-7. doi: 10.1007/s00405-006-0222-8. Epub 2007 Feb 14.

Abstract

There is a lot of scepticism surrounding laryngopharyngeal reflux (LPR). Symptoms such as globus pharyngeus, constant throat clearing, chronic cough, idiopathic hoarseness, catarrh and choking episodes may be reflux-related. The aim of this survey was to highlight current treatment trends in LPR. Questionnaires were emailed to 260 members of the British Academy of Otolaryngology-Head and Neck surgery (BAO-HNS). Survey recipients were asked about type, duration and dose of antireflux treatment and length of follow-up appointments, if any. Finally, they were asked about awareness of any reflux symptom and reflux sign questionnaires. Survey response rate was 60%. The vast majority of the otolaryngologists surveyed believe in laryngopharyngeal reflux (90%) and more than 50% prescribe proton pump inhibitors (PPIs). The preferred duration of treatment is 2 months (37%). Only a minority will prescribe PPIs for 6 months or more. Most otolaryngologists will give the standard GORD dose (70%) (once daily) and only a few (20%) will prescribe more aggressive and prolonged doses. The commonest symptoms for which proton pump inhibitors are prescribed are globus (73%), followed by choking episodes (66%) and chronic cough (62%). If LPR is suspected, most of the otolaryngologists will follow-up the patients (61%) and approximately one third (31%) will discharge them back to the general practitioners. Only eight-percent 8% will refer to gastroenterologists. The three commonest laryngoscopic signs that makes them suspect LPR are erythema of the arytenoids (86%) or the vocal cords (57%) and granulomas (42%). The majority of the otolaryngologists (94%) do not use popular questionnaires such as the RFS or RSI. Despite the controversy surrounding laryngopharyngeal reflux, our results suggest that the majority of the otolaryngologists surveyed believe in LPR and attempt to treat it. Interesting findings are: the duration of treatment, the doses used, the length of follow-ups or the lack of, and the fact that the majority does not request any specific diagnostic tests. "symptoms and signs" questionnaires are rarely used.

摘要

关于喉咽反流(LPR)存在诸多质疑。诸如咽异感症、持续清嗓、慢性咳嗽、特发性声音嘶哑、黏膜炎和呛咳发作等症状可能与反流有关。本次调查的目的是突出当前LPR的治疗趋势。问卷通过电子邮件发送给了英国耳鼻喉科-头颈外科学会(BAO-HNS)的260名成员。调查对象被问及抗反流治疗的类型、持续时间和剂量以及随访预约的时长(若有)。最后,他们被问及是否知晓任何反流症状和反流体征问卷。调查回复率为60%。绝大多数接受调查的耳鼻喉科医生相信喉咽反流(90%),超过50%的医生会开具质子泵抑制剂(PPI)。首选的治疗持续时间为2个月(37%)。只有少数医生会开具PPI达6个月或更长时间。大多数耳鼻喉科医生会给予标准的胃食管反流病剂量(70%)(每日一次),只有少数(20%)会开具更积极、持续时间更长的剂量。开具质子泵抑制剂最常见的症状是咽异感症(73%),其次是呛咳发作(66%)和慢性咳嗽(62%)。如果怀疑有LPR,大多数耳鼻喉科医生会对患者进行随访(61%),约三分之一(31%)会让患者回到全科医生处。只有8%的医生会转诊给胃肠病学家。使他们怀疑LPR的三个最常见的喉镜检查体征是杓状软骨红斑(86%)或声带红斑(57%)以及肉芽肿(42%)。大多数耳鼻喉科医生(94%)不使用诸如反流症状评分(RFS)或反流指数量表(RSI)等常用问卷。尽管围绕喉咽反流存在争议,但我们的结果表明,大多数接受调查的耳鼻喉科医生相信LPR并试图进行治疗。有趣的发现有:治疗持续时间、使用的剂量、随访时长或缺乏随访,以及大多数医生不要求进行任何特定诊断测试这一事实。“症状和体征”问卷很少被使用。

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