Ebersole John S, Hawes-Ebersole Susan
Department of Neurology, Adult Epilepsy Center, The University of Chicago, Chicago, Illinois 60637, USA.
J Clin Neurophysiol. 2007 Apr;24(2):120-9. doi: 10.1097/WNP.0b013e31803ece13.
Routine clinical interpretation of EEG using visual inspection of traces is a time-honored, but simplistic, form of analysis. This is particularly true in attempts to localize an epileptogenic focus by means of EEG spike or seizure waveforms. Improved understanding of the cortical substrates of these potentials has allowed us to identify their likely cerebral origins through spatio-temporal analysis of scalp voltage fields. Equivalent dipole modeling is one such technique. Although an imperfect representation of spike or seizure sources, proper interpretation of dipole models can lead to a far better characterization of their localization and propagation. Modern techniques of 3-D MRI reconstruction and realistic head models have both improved localization accuracy and provided a means of displaying results in an image of the individual's brain.
通过目视检查脑电图迹线进行脑电图的常规临床解读是一种历史悠久但过于简单的分析形式。在试图通过脑电图棘波或癫痫发作波形定位致痫灶时尤其如此。对这些电位的皮质基质有了更好的理解，使我们能够通过头皮电压场的时空分析来确定它们可能的脑起源。等效偶极子建模就是这样一种技术。尽管偶极子模型对棘波或癫痫发作源的表示并不完美，但对偶极子模型的正确解读可以更好地描述它们的定位和传播。现代三维磁共振成像重建技术和逼真的头部模型既提高了定位准确性，又提供了在个体大脑图像中显示结果的方法。
