Ben Saad H, Ben Attia Saafi R, Rouatbi S, Ben Mdella S, Garrouche A, Zbidi A, Hayot M, Tabka Z
Service de physiologie et des explorations fonctionnelles, EPS Farhat Hached, Sousse, Tunisia.
Rev Mal Respir. 2007 Mar;24(3 Pt 1):323-30. doi: 10.1016/s0761-8425(07)91064-5.
There is no clear consensus as to what constitutes an obstructive ventilatory defect (OVD). According to the American Thoracic Society and European Respiratory Society, it is defined as being when the ratio of the forced expiratory volume (FEV1) and the slow expiratory vital capacity (VC) is below the lower limit of normal (LLN). According to the Global initiative for chronic Obstructive Lung Disease and the British Thoracic Society, it is an FEV1/forced expiratory vital capacity (FVC)<0.70 and an FEV1<80%. In addition, in daily practice, the OVD is diagnosed by a "Fixed ratio" FEV1/FVC<0.70 or<LLN. The aim of this study is to determine, according to the different recommendations, the percentage of subjects having an OVD among them addressed for suspicion of chronic obstructive pulmonary disease.
A medical questionnaire was administered and anthropometric data were collected. The expiratory flows and pulmonary volumes were measured by a body plethysmograph.
121 (81%) subjects among the 150 examined were included. The percentage of subjects having an OVD was 56.1% (FEV1/VC<LLN), 54.1% (FEV1/FVC<0.70), 48.7% (FEV1/FVC<0.70 and FEV1<80%), and 47.8% (FEV1/FVC<LLN).
The prevalence of obstructive ventilatory defect in a population depends on the definition chosen.
对于什么构成阻塞性通气功能障碍（OVD）尚无明确共识。根据美国胸科学会和欧洲呼吸学会的定义，当用力呼气量（FEV1）与慢肺活量（VC）的比值低于正常下限（LLN）时即被定义为阻塞性通气功能障碍。根据慢性阻塞性肺疾病全球倡议组织和英国胸科学会的定义，阻塞性通气功能障碍是指FEV1/用力肺活量（FVC）<0.70且FEV1<80%。此外，在日常实践中，阻塞性通气功能障碍通过“固定比值”FEV1/FVC<0.70或<LLN来诊断。本研究的目的是根据不同的推荐标准，确定因疑似慢性阻塞性肺疾病而接受检查的人群中存在阻塞性通气功能障碍的受试者百分比。
发放一份医学问卷并收集人体测量数据。通过体容积描记法测量呼气流量和肺容积。
150名接受检查的受试者中有121名（81%）被纳入研究。存在阻塞性通气功能障碍的受试者百分比分别为：56.1%（FEV1/VC<LLN）、54.1%（FEV1/FVC<0.70）、48.7%（FEV1/FVC<0.70且FEV1<80%）以及47.8%（FEV1/FVC<LLN）。
人群中阻塞性通气功能障碍的患病率取决于所选用的定义。
