Salim A S
Department of Surgery, Royal Infirmary, Perth.
Ann R Coll Surg Engl. 1991 Mar;73(2):119-23.
This prospective randomised study examined the possibility of early resumption of oral hydration and discontinuation of intravenous fluid replacement after emergency or elective abdominal surgery. Following elective cholecystectomy alone or with a choledocholithotomy or an emergency Hartmann's procedure for large bowel obstruction, patients were randomised to early oral hydration (sips of water for 12 h followed by free fluids by mouth for 24 h, when oral intake of food was allowed--intravenous hydration was discontinued 6 h after starting the intake of free fluids orally) or conventional intravenous hydration (intravenous hydration and an oral regimen of water as follows: sips every hour for 12 h, 30 ml every hour for 24 h, 60 ml every hour for 24 h, 90 ml every hour for 24 h, free fluids for 12 h, when food was allowed--intravenous hydration was discontinued 6 h after starting the free fluids). The two regimens were equally effective in maintaining fluid balance and normal plasma and urinary electrolytes without any observed differences in biochemical or metabolic values. Each of free fluids by mouth, discontinuation of intravenous hydration, and consumption of solid food were achieved in the patients on early oral hydration at time periods significantly shorter than those attained with the conventional regimen (P less than 0.001). Similarly, patients on the latter regimen were hospitalised for significantly longer times than those on early oral hydration (P less than 0.001). Early oral hydration after biliary surgery or a Hartmann's procedure effectively maintains fluid balance and has advantages over the conventional intravenous hydration regimen.
这项前瞻性随机研究探讨了急诊或择期腹部手术后早期恢复口服补液及停止静脉补液的可能性。在单独行择期胆囊切除术、或合并胆总管切开取石术、或因大肠梗阻行急诊哈特曼手术之后,患者被随机分为早期口服补液组(术后12小时小口饮水,之后24小时可自由经口摄入液体,此时允许经口进食——开始经口自由摄入液体6小时后停止静脉补液)或传统静脉补液组(静脉补液并采用如下口服饮水方案:12小时内每小时小口饮水,24小时内每小时30毫升,24小时内每小时60毫升,24小时内每小时90毫升,12小时自由摄入液体,此时允许进食——开始自由摄入液体6小时后停止静脉补液)。两种方案在维持液体平衡以及正常血浆和尿液电解质方面同样有效,在生化或代谢值方面未观察到任何差异。早期口服补液组患者在经口自由摄入液体、停止静脉补液以及食用固体食物的时间上均显著短于传统方案组(P<0.001)。同样,传统方案组患者的住院时间显著长于早期口服补液组患者(P<0.001)。胆道手术或哈特曼手术后早期口服补液能有效维持液体平衡,且优于传统静脉补液方案。