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腹部手术后静脉补液的持续时间:一项前瞻性随机研究。

Duration of intravenous fluid replacement after abdominal surgery: a prospective randomised study.

作者信息

Salim A S

机构信息

Department of Surgery, Royal Infirmary, Perth.

出版信息

Ann R Coll Surg Engl. 1991 Mar;73(2):119-23.

PMID:1741806
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2499386/
Abstract

This prospective randomised study examined the possibility of early resumption of oral hydration and discontinuation of intravenous fluid replacement after emergency or elective abdominal surgery. Following elective cholecystectomy alone or with a choledocholithotomy or an emergency Hartmann's procedure for large bowel obstruction, patients were randomised to early oral hydration (sips of water for 12 h followed by free fluids by mouth for 24 h, when oral intake of food was allowed--intravenous hydration was discontinued 6 h after starting the intake of free fluids orally) or conventional intravenous hydration (intravenous hydration and an oral regimen of water as follows: sips every hour for 12 h, 30 ml every hour for 24 h, 60 ml every hour for 24 h, 90 ml every hour for 24 h, free fluids for 12 h, when food was allowed--intravenous hydration was discontinued 6 h after starting the free fluids). The two regimens were equally effective in maintaining fluid balance and normal plasma and urinary electrolytes without any observed differences in biochemical or metabolic values. Each of free fluids by mouth, discontinuation of intravenous hydration, and consumption of solid food were achieved in the patients on early oral hydration at time periods significantly shorter than those attained with the conventional regimen (P less than 0.001). Similarly, patients on the latter regimen were hospitalised for significantly longer times than those on early oral hydration (P less than 0.001). Early oral hydration after biliary surgery or a Hartmann's procedure effectively maintains fluid balance and has advantages over the conventional intravenous hydration regimen.

摘要

这项前瞻性随机研究探讨了急诊或择期腹部手术后早期恢复口服补液及停止静脉补液的可能性。在单独行择期胆囊切除术、或合并胆总管切开取石术、或因大肠梗阻行急诊哈特曼手术之后,患者被随机分为早期口服补液组(术后12小时小口饮水,之后24小时可自由经口摄入液体,此时允许经口进食——开始经口自由摄入液体6小时后停止静脉补液)或传统静脉补液组(静脉补液并采用如下口服饮水方案:12小时内每小时小口饮水,24小时内每小时30毫升,24小时内每小时60毫升,24小时内每小时90毫升,12小时自由摄入液体,此时允许进食——开始自由摄入液体6小时后停止静脉补液)。两种方案在维持液体平衡以及正常血浆和尿液电解质方面同样有效,在生化或代谢值方面未观察到任何差异。早期口服补液组患者在经口自由摄入液体、停止静脉补液以及食用固体食物的时间上均显著短于传统方案组(P<0.001)。同样,传统方案组患者的住院时间显著长于早期口服补液组患者(P<0.001)。胆道手术或哈特曼手术后早期口服补液能有效维持液体平衡,且优于传统静脉补液方案。

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Duration of intravenous fluid replacement after abdominal surgery: a prospective randomised study.腹部手术后静脉补液的持续时间:一项前瞻性随机研究。
Ann R Coll Surg Engl. 1991 Mar;73(2):119-23.
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2
Immediate discontinuation of intravenous fluids after common surgical procedures.常见外科手术后立即停止静脉输液。
J Family Community Med. 2000 Jan;7(1):69-73.
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Intravenous fluid restriction after major abdominal surgery: a randomized blinded clinical trial.腹部大手术后静脉输液限制:一项随机双盲临床试验。
Trials. 2009 Jul 7;10:50. doi: 10.1186/1745-6215-10-50.
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Effects of intravenous fluid restriction on postoperative complications: comparison of two perioperative fluid regimens: a randomized assessor-blinded multicenter trial.静脉输液限制对术后并发症的影响:两种围手术期液体方案的比较:一项随机评估者盲法多中心试验
Ann Surg. 2003 Nov;238(5):641-8. doi: 10.1097/01.sla.0000094387.50865.23.
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Randomized comparison of oral and intravenous fluid regimens after gallbladder surgery.胆囊切除术后口服与静脉补液方案的随机对照比较。
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Immediate enteral feeding after gastro-intestinal resection. Fluid regimen given to control group is increasingly being abandoned.胃肠道切除术后立即肠内喂养。给予对照组的液体疗法越来越被摒弃。
BMJ. 1996 Jul 27;313(7051):230. doi: 10.1136/bmj.313.7051.230a.
7
Patient tolerance of the early introduction of oral fluids after laparotomy.剖腹术后早期引入口服液体时患者的耐受性
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