Khoo D, Feigenbaum S L, McClure R D
Department of Urology, University of California School of Medicine, San Francisco 94143-0738.
Am J Reprod Immunol. 1991 Aug;26(1):11-6. doi: 10.1111/j.1600-0897.1991.tb00694.x.
Because the immunobead antisperm antibody test (IBT) is difficult to learn and results are heavily operator-dependent, we compared findings on IBT with those of SpermMAR and SpermCheck in 58 patients to determine whether the latter two tests could demonstrate improved screening ability. Assays performed on both sperm and serum (i.e., direct and indirect) yielded 100% positive predictive values when IBT was used as the standard. Both SpermCheck and SpermMAR are easier to perform, and, as the former has a slightly greater sensitivity, we recommend SpermCheck for the detection of immunologic infertility.
由于免疫珠抗精子抗体检测（IBT）难以掌握且结果严重依赖操作人员，我们对58例患者的IBT结果与精子膜抗体反应（SpermMAR）和精子检测（SpermCheck）结果进行了比较，以确定后两项检测是否具有更好的筛查能力。以IBT作为标准时，对精子和血清进行的检测（即直接和间接检测）均产生了100%的阳性预测值。SpermCheck和SpermMAR操作起来都更简便，且由于前者的灵敏度略高，我们推荐使用SpermCheck来检测免疫性不孕。
