Olsen J, Overvad K, Frische G
Institute of Social Medicine, University of Aarhus, Denmark.
Epidemiology. 1991 Sep;2(5):370-4. doi: 10.1097/00001648-199109000-00011.
We studied the effect of coffee consumption on birthweight, preterm births, and congenital malformations. From April 1985 to April 1987, 11,858 pregnant women out of 13,815 in two Danish cities responded to a mailed questionnaire on eating and drinking habits during pregnancy. Data on pregnancy outcomes were recorded from medical files. Maternal coffee consumption of four cups a day or more was associated with a moderate decrease in birthweight, especially among smokers. The associations between coffee consumption and preterm births or congenital malformations were very weak.
我们研究了咖啡摄入量对出生体重、早产和先天性畸形的影响。1985年4月至1987年4月，丹麦两个城市的13,815名孕妇中有11,858名回复了一份关于孕期饮食习惯的邮寄问卷。妊娠结局数据从医疗档案中记录。每天饮用四杯或更多咖啡与出生体重适度降低有关，尤其是在吸烟者中。咖啡摄入量与早产或先天性畸形之间的关联非常微弱。
