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以风湿性多肌痛为特征的迟发性未分化脊柱关节炎:7例病例描述

Late onset undifferentiated spondyloarthritis presenting with polymyalgia rheumatica features: description of seven cases.

作者信息

Olivieri Ignazio, Garcia-Porrua Carlos, Padula Angela, Cantini Fabrizio, Salvarani Carlo, Gonzalez-Gay Miguel A

机构信息

Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, 85100 Potenza, Italy.

出版信息

Rheumatol Int. 2007 Aug;27(10):927-33. doi: 10.1007/s00296-007-0331-8. Epub 2007 Apr 11.

Abstract

To underline the importance of considering a diagnosis of undifferentiated spondyloarthritis (uSpA) in patients presenting polymyalgia rheumatica (PMR) features. All patients with late onset uSpA meeting criteria for PMR at the onset of their disease seen in the Rheumatology Division of Xeral-Calde Hospital of Lugo, Spain during a 5 year period, and in the Rheumatology Department of Lucania, Italy in a two and a half year period, were studied. Six patients with late onset uSpA showing PMR symptoms at the onset were seen during the study periods in the two centres. Another patient had previously been observed in Lugo in a study dealing with the spectrum of conditions mimicking PMR. Of the seven patients, five had manifestations of SpA at the beginning of the disease and two developed these in the following 6 months. All seven met the Amor and/or the ESSG criteria for classifying and diagnosing SpA. The possibility that late onset uSpA may have PMR-like features at the beginning of the disease should be taken into account. The diagnosis is not difficult if the entire clinical spectrum of SpA is considered.

摘要

强调在表现为风湿性多肌痛(PMR)特征的患者中考虑未分化脊柱关节炎(uSpA)诊断的重要性。对西班牙卢戈市塞拉尔 - 卡尔德医院风湿病科在5年期间以及意大利卢卡尼亚风湿病科在两年半期间所诊治的所有发病时符合PMR标准的晚发性uSpA患者进行了研究。在这两个中心的研究期间,共发现6例发病时表现为PMR症状的晚发性uSpA患者。在卢戈市之前的一项关于模拟PMR病症谱的研究中还观察到另外1例患者。这7例患者中,5例在疾病初期就有脊柱关节炎(SpA)表现,另外2例在接下来的6个月内出现这些表现。所有7例均符合用于分类和诊断SpA的阿穆尔(Amor)和/或欧洲脊柱关节病研究组(ESSG)标准。应考虑到晚发性uSpA在疾病初期可能具有类似PMR特征的可能性。如果考虑SpA的整个临床谱,诊断并不困难。

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