Staikowsky F, Le Roux K, Schuffenecker I, Laurent P, Grivard P, Develay A, Michault A
Service des Urgences, Groupe Hospitalier Sud Réunion, La Réunion, France.
Epidemiol Infect. 2008 Feb;136(2):196-206. doi: 10.1017/S0950268807008424. Epub 2007 Apr 16.
Réunion Island (Indian Ocean) has been suffering from its first known Chikungunya virus (CHIKV) epidemic since February 2005. To achieve a better understanding of the disease, a questionnaire was drawn up for hospital staff members and their household. CHIKV infected about one-third of the studied population, the proportion increasing with age and being higher in women. Presence of a garden was associated with CHIKV infection. The geographical distribution of cases was concordant with insect vector Aedes albopictus distribution. The main clinical signs were arthralgia and fever. The disease evolved towards full recovery in 34.4% of cases, a relapse in 55.6%, or a chronic form in 10%. Paracetamol was used as a painkiller in 95% of cases, sometimes associated with non-steroidal anti-inflammatory drugs, corticoids, or traditional herbal medicine. The survey provided valuable information on the factors that favour transmission, the clinical signs, the importance of relapses and the therapies used.
留尼汪岛（印度洋）自2005年2月以来一直遭受其首次已知的基孔肯雅病毒（CHIKV）疫情。为了更好地了解这种疾病，为医院工作人员及其家庭成员编制了一份调查问卷。CHIKV感染了约三分之一的研究人群，这一比例随年龄增长而增加，且女性中的比例更高。拥有花园与CHIKV感染有关。病例的地理分布与病媒白纹伊蚊的分布一致。主要临床症状为关节痛和发热。34.4%的病例病情逐渐完全康复，55.6%复发，10%发展为慢性形式。95%的病例使用对乙酰氨基酚作为止痛药，有时与非甾体抗炎药、皮质类固醇或传统草药联合使用。该调查提供了关于有利于传播的因素、临床症状、复发的重要性以及所使用治疗方法的宝贵信息。
