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4D 光谱空间电子顺磁共振成像的模拟。

Simulation of 4D spectral-spatial EPR images.

作者信息

Ahn Kang-Hyun, Halpern Howard J

机构信息

Department of Radiation and Cellular Oncology, University of Chicago, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.

出版信息

J Magn Reson. 2007 Jul;187(1):1-9. doi: 10.1016/j.jmr.2007.02.013. Epub 2007 Mar 1.

Abstract

Electron paramagnetic resonance imaging (EPRI) can be modeled by the forward projection of a 4D synthetic spectral-spatial phantom. We developed a simulation tool for EPRI and carried out a quantitative comparison between simulation and experiment, focusing on the signal and noise characteristics. The signal height in the simulation was compared to that in the experimental projections at gradients of different magnitudes and directions. We investigated the noise power spectrum of an EPR imager and incorporated it into the simulation. The signal and noise modeling of the simulation achieved the same performance as the EPR imager. Using this simulation, various sampling schemes were tried to find an optimized parameter set under the customized noise model of this EPR imager.

摘要

电子顺磁共振成像(EPRI)可以通过4D合成光谱空间体模的正向投影来建模。我们开发了一种用于EPRI的模拟工具,并针对信号和噪声特性,对模拟和实验进行了定量比较。在不同大小和方向的梯度下,将模拟中的信号高度与实验投影中的信号高度进行了比较。我们研究了EPR成像仪的噪声功率谱,并将其纳入模拟。模拟的信号和噪声建模与EPR成像仪具有相同的性能。利用该模拟,尝试了各种采样方案,以在该EPR成像仪的定制噪声模型下找到优化的参数集。

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