Al-Ghamdi Mohammed Y, Bedi Anil, Reddy S Bharati, Tanton Ronald T, Peltekian Kevork M
Division of Gastroenterology, Dalhousie University, Halifax, Nova Scotia, Canada.
Dig Dis Sci. 2007 Sep;52(9):2261-4. doi: 10.1007/s10620-006-9734-8. Epub 2007 Apr 12.
Malignancy, surgical trauma, cirrhosis and tuberculosis account for more than 95% of causes for chylous ascites. We report a case of persistent chylous ascites following acute pancreatitis that responded to parenteral nutrition and octreotide. A 50 year-old male was diagnosed with acute alcoholic pancreatitis after presenting with typical abdominal pain, and elevated amylase and lipase. The acute symptoms resolved within one week. Four weeks later he started developing increased abdominal girth. Examination revealed the presence of shifting dullness and paracentesis confirmed diagnosis of chylous ascites. Investigations for the common causes of chylous ascites were negative. Laparoscopy confirmed the presence of fat necrosis within mesenteric lymph nodes linking the chylous ascites to the episode of pancreatitis. The Chylous ascites was resistant to the usual medical therapy, but responded only to the combination of octreotide and total parenteral nutrition with complete resolution of ascites in 8 weeks. This case of chylous ascites secondary to pancreatitis represents an uncommon presentation with effective management resulting in a dramatic response.
恶性肿瘤、手术创伤、肝硬化和结核病占乳糜性腹水病因的95%以上。我们报告一例急性胰腺炎后持续性乳糜性腹水病例,该病例对肠外营养和奥曲肽治疗有效。一名50岁男性在出现典型腹痛、淀粉酶和脂肪酶升高后被诊断为急性酒精性胰腺炎。急性症状在一周内缓解。四周后,他开始出现腹围增加。检查发现有移动性浊音,腹腔穿刺术确诊为乳糜性腹水。对乳糜性腹水常见病因的检查均为阴性。腹腔镜检查证实肠系膜淋巴结内存在脂肪坏死,这将乳糜性腹水与胰腺炎发作联系起来。乳糜性腹水对常规药物治疗无效,但仅对奥曲肽和全肠外营养联合治疗有反应,腹水在8周内完全消退。这例胰腺炎继发乳糜性腹水是一种罕见的表现,有效治疗后反应显著。