Steinman Michael A, Chren Mary-Margaret, Landefeld C Seth
Division of Geriatrics, San Francisco VA Medical Center and the University of California, San Francisco, CA 94121, USA.
J Gen Intern Med. 2007 May;22(5):645-8. doi: 10.1007/s11606-006-0074-3.
The use of brand rather than generic names for medications can increase health care costs. However, little is known at a national level about how often physicians refer to drugs using their brand or generic names.
To evaluate how often physicians refer to drugs using brand or generic terminology.
We used data from the 2003 National Ambulatory Medical Care Survey (NAMCS), a nationally representative survey of 25,288 community-based outpatient visits in the United States. After each visit, patient medications were recorded on a survey encounter form by the treating physician or transcribed from office notes.
Our main outcome measure was the frequency with which medications were recorded on the encounter form using their brand or generic names.
For 20 commonly used drugs, the median frequency of brand name use was 98% (interquartile range, 81-100%). Among 12 medications with no generic competition at the time of the survey, the median frequency of brand name use was 100% (range 92-100%). Among 8 medications with generic competition at the time of the survey ("multisource" drugs), the median frequency of brand name use was 79% (range 0-98%; P < .001 for difference between drugs with and without generic competition).
Physicians refer to most medications by their brand names, including drugs with generic formulations. This may lead to higher health care costs by promoting the use of brand-name products when generic alternatives are available.
使用药品的品牌名而非通用名会增加医疗保健成本。然而,在国家层面上,对于医生使用品牌名或通用名提及药物的频率了解甚少。
评估医生使用品牌名或通用术语提及药物的频率。
我们使用了2003年国家门诊医疗护理调查(NAMCS)的数据,这是一项对美国25,288次社区门诊就诊进行的具有全国代表性的调查。每次就诊后,治疗医生会在调查问诊表上记录患者的用药情况,或从病历记录中转录。
我们的主要测量指标是在问诊表上使用品牌名或通用名记录药物的频率。
对于20种常用药物,使用品牌名的频率中位数为98%(四分位间距,81 - 100%)。在调查时没有通用名竞品的12种药物中,使用品牌名的频率中位数为100%(范围92 - 100%)。在调查时有通用名竞品的8种药物(“多源”药物)中,使用品牌名的频率中位数为79%(范围0 - 98%;有通用名竞品和无通用名竞品的药物之间差异P <.001)。
医生大多使用品牌名提及药物,包括有通用剂型的药物。当有通用名替代产品时,这可能会通过促进品牌名产品的使用导致更高的医疗保健成本。